Results 241 to 250 of about 1,050,824 (300)

Genomic epidemiology and molecular characterization of <i>Streptococcus pyogenes</i> isolates from pediatric infections in Beijing, China. [PDF]

Microbiol Spectr
Song Z, Zhou L, Xu W, Tian M, Yu L, Zhang X, Song R, Li J, Ma L.   +8 more
europepmc   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Phylo-Plex: a phylogenetically informed, low-cost amplicon sequencing platform for deployable high-resolution genomic epidemiology. [PDF]

Nat Commun
Beale MA, Shetty V, Ambridge KE, Lacey G, Dougan S, Roberts-Sengier W, Sampher B, Lassalle F, Dorman MJ, Mahlangu MP, Venter JME, Da Costa Dias B, Chipinduro M, Washaya TM, Rodgers L, Makamure B, Dauya E, Marks M, Müller EE, Ferrand RA, Thomson NR.   +20 more
europepmc   +1 more source

Epigenetically Regulated NOX4/NRF2 Axis Mediates PM2.5‐Induced Ferroptosis and Inflammatory Response in Membranous Nephropathy

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aims to explore the involvement and mechanism of ferroptosis in particulate matter 2.5 (PM2.5)–induced membranous nephropathy (MN) progression. A cationic bovine serum albumin (cBSA)–induced mouse model of MN was established, followed by PM2.5 exposure.
Yanhong Gao, Yinfeng Guo, Shaoyan Xu, Min Zhang, Yanxia Rui, Shujun Pan, Changhua Zhou, Jianxiang Chen, Henglan Wu   +8 more
wiley   +1 more source

Transdisciplinary training to address challenges in genomic epidemiology of infectious diseases. [PDF]

Front Public Health
Hong SL, Stockman M, Nova Blanco JR, Van Cleemput C, Ahouidi A, Armién B, Bento A, Bollen N, Conde Pereira C, Freitas C, Hofstra M, Jordan MR, Kashima S, Gonçalves CCM, Campelo de Albuquerque E Melo CF, Nahata K, de Oliveira EC, Parra L, Saenz C, de Souza W, Stanojevic M, Rabinowitz PM, Vandamme AM.   +22 more
europepmc   +1 more source

Hematological and Genotoxic Effects of Subchronic Oral Exposure to a Mancozeb‐Based Fungicide in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo, Natanael Vaz Crisóstomo Peixoto, Paula Soares Nakamura, Cecília Müller Wodzik, Lucas Ribeiro Maia dos Santos, Fábio Vieira de Andrade Borges, Lara Cândida de Sousa Machado, Jéssica Gardone Vitório, Renata Mazaro e Costa, Mônica Rodrigues Ferreira Machado, Walter Dias Júnior   +10 more
wiley   +1 more source

The SARS-CoV-2 Integrated Genomic Epidemiology Database (IGED): Linking viral genomes with patient-level metadata to advance statewide genomic surveillance in California. [PDF]

PLOS Digit Health
Elder J, Ryder R, Panditrao M, Grosgebauer K, Katz R, Tello L, Carroll E, Borthwick D, Kaur C, Smith R, Shiau V, Wheeler W, Reilly E, Myers J, Nelson L, Lim E, Arunleung P, Baylis E, Gilliam S, Hennessy-Burt T, Bregman B, Silver E, Kapsak C, Wright S, Leon T, Bell J, Morales C, Wadford DA.   +27 more
europepmc   +1 more source

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

Estimating the contribution to transmission of asymptomatic tuberculosis from population-based genomic epidemiology studies. [PDF]

Emerg Microbes Infect
Li M, Cai L, Gao Q.
europepmc   +1 more source

Genetic and Clinical Characteristics of Thalassemia Trait and Construction of LASSO‐Based Model for Its Differentiating From Iron Deficiency Anemia in Northern China

Journal of Clinical Laboratory Analysis, EarlyView.
This study revealed a β‐thalassemia‐trait‐dominated genetic spectrum in Northern‐Chinese patients with microcytic hypochromic anemia, with _αSEA/αα, HBB:c.316_197C>T and HBB:c.124_127delTTCT being the most prevalent α‐ and β‐globin genotypes. Using LASSO regression, we constructed a nomogram based on four routine complete‐blood‐count parameters (RBC ...
Wen‐jie Yu, Feng‐qi Zhang, Jia‐feng Niu, Rui Ma, Yin‐ting Ma, Guang‐ping Li, Yan Long   +6 more
wiley   +1 more source