Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko+2 more
wiley +1 more source
Genomic prediction powered by multi-omics data. [PDF]
Montesinos-López OA+8 more
europepmc +1 more source
The prediction of disease risk in genomic medicine
Wayne Hall+2 more
openalex +2 more sources
A general integrative genomic feature transcription factor binding site prediction method applied to analysis of USF1 binding in cardiovascular disease [PDF]
Tianyuan Wang+7 more
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Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita+3 more
wiley +1 more source
Revisiting the Plasmodium falciparum RIFIN family: from comparative genomics to 3D-model prediction [PDF]
Emanuele Bultrini+6 more
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Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley +1 more source
Harnessing genomic prediction in Brassica napus through a nested association mapping population. [PDF]
Perumal S+16 more
europepmc +1 more source
Live birth after polar body array comparative genomic hybridization prediction of embryo ploidy—the future of IVF? [PDF]
Simon Fishel+10 more
openalex +1 more source
Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia+20 more
wiley +1 more source