Results 361 to 370 of about 3,983,457 (419)

Potential negative effects of genomic selection. [PDF]

J Anim Sci
Misztal I, Lourenco D.
europepmc   +1 more source

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

Editorial: Plant adaptation to climate change using genomic selection and high-throughput technologies. [PDF]

Front Genet
Ornella LA, Broccanello C, Balzarini M.
europepmc   +1 more source

Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy

Advanced Science, EarlyView.
This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan, Qianyu Li, Guoquan Yan, Yifei Qian, Wenyun Guo, Songling Li, Fan Wang, Wanjing Shang, Zijun Zhu, Di Ge, Yanan Wang, Yanfeng Liu   +11 more
wiley   +1 more source

Genomic selection in forest trees comes to life: unraveling its potential in an advanced four-generation Eucalyptus grandis population. [PDF]

Front Plant Sci
Duarte D, Jurcic EJ, Dutour J, Villalba PV, Centurión C, Grattapaglia D, Cappa EP.   +6 more
europepmc   +1 more source

Malignant Hepatoblast‐Like Cells Sustain Stemness via IGF2‐Dependent Cholesterol Accumulation in Hepatoblastoma

Advanced Science, EarlyView.
Hepatoblastoma, an aggressive childhood liver tumor, origins from malignant hepatoblast‐like cells. Single‐cell analysis reveals IGF2‐driven pathways promoting malignancy. Targeting these pathways offers promising treatments, with serum IGF2 as a potential diagnostic biomarker.
Miao Ding, Siwei Mao, Han Wu, Sijia Fang, Ni Zhen, Tianshu Chen, Jiabei Zhu, Xiaochen Tang, Xiaoyang Wang, Fenyong Sun, Guoqing Zhu, Qiuhui Pan, Ji Ma   +12 more
wiley   +1 more source

The Evolution and Role of Molecular Tools in Measuring Diversity and Genomic Selection in Livestock Populations (Traditional and Up-to-Date Insights): A Comprehensive Exploration. [PDF]

Vet Sci
Husien HM, Saleh AA, Hassanine NNAM, Rashad AMA, Sharaby MA, Mohamed AZ, Abdelhalim H, Hafez EE, Essa MOA, Adam SY, Chen N, Wang M.   +11 more
europepmc   +1 more source

Integrating Genomic Selection and a Genome-Wide Association Study to Improve Days Open in Thai Dairy Holstein Cattle: A Comprehensive Genetic Analysis. [PDF]

Animals (Basel)
Fathoni A, Boonkum W, Chankitisakul V, Buaban S, Duangjinda M.   +4 more
europepmc   +1 more source

Udder, Claw, and Reproductive Health in Genomic Selection of the Czech Holstein. [PDF]

Animals (Basel)
Krupová Z, Kašná E, Zavadilová L, Krupa E, Bauer J, Wolfová M.   +5 more
europepmc   +1 more source

QTL mapping and genomic selection of stem and branch diameter in soybean (Glycine max L.). [PDF]

Front Plant Sci
Wang J, Yang Q, Chen Y, Liu K, Zhang Z, Xiong Y, Yu H, Yu Y, Wang J, Song J, Qiu L.   +10 more
europepmc   +1 more source