Results 271 to 280 of about 2,130,247 (378)

Building capability for clinician-led genomic change: insights from use and non-use of a theory-informed model for change. [PDF]

Front Genet
Martyn M, Clarke A, Do T, Dawson-McClaren B, Gaff C.   +4 more
europepmc   +1 more source

Genomics and Biological Activity of Neutrophil Gelatinase-Associated Lipocalin in Several Clinical Settings [PDF]

, 2013
Grazia Maria Virzì, Anna Clementi, Massimo de Cal, Dinna N. Cruz, Claudio Ronco   +4 more
openalex   +1 more source

Population genomics of Bronze Age Eurasia

Nature, 2015
M. Allentoft, M. Sikora, K. Sjögren, Simon Rasmussen, M. Rasmussen, Jesper T. Stenderup, P. B. Damgaard, Hannes Schroeder, Torbjörn Ahlström, L. Vinner, Anna-Sapfo Malaspinas, A. Margaryan, Tom Higham, D. Chivall, N. Lynnerup, L. Harvig, J. Baron, P. D. Casa, P. Dąbrowski, Paul R. Duffy, Alexander V. Ebel, A. Epimakhov, K. Frei, M. Furmanek, Tomasz Gralak, A. Gromov, S. Gronkiewicz, G. Grupe, Tamás Hajdu, Radosław Jarysz, V. Khartanovich, A. Khokhlov, V. Kiss, J. Kolář, A. Kriiska, Irena Lasak, C. Longhi, George C. McGlynn, A. Merkevičius, Inga Merkytė, M. Metspalu, R. Mkrtchyan, V. Moiseyev, László Paja, G. Pálfi, Dalia Pokutta, Łukasz Pospieszny, T. D. Price, Lehti Saag, M. Sablin, N. Shishlina, V. Smrcka, V. Soenov, Vajk Szeverényi, Gusztáv Tóth, S. Trifanova, Liivi Varul, M. Vicze, L. Yepiskoposyan, V. Zhitenev, L. Orlando, Thomas Sicheritz-Pontén, S. Brunak, R. Nielsen, K. Kristiansen, E. Willerslev   +65 more
semanticscholar   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco, Mònica Roldán, Yalda Jamshidi, Ioannis Georvasilis, Rocío Jadraque Rodríguez, Reza Boostani, Ali Shoeibi, Lluís Armengol, Anna Codina, Ehsan Ghayoor Karimiani, Cristina Hernando‐Davalillo, Loreto Martorell, María Luisa Ramírez Almaraz, Jordi Muchart, Carlos Ortez, Andrés Nascimento, Roser Urreizti, Daniel Natera‐de Benito, Mercedes Serrano   +18 more
wiley   +1 more source

Cosmetogenomics unveiled: a systematic review of AI, genomics, and the future of personalized skincare. [PDF]

Front Artif Intell
Haykal D, Flament F, Amar D, Cartier H, Kourosh AS, Lee DH, Rowland-Payne C.   +6 more
europepmc   +1 more source

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich, Tilman Schneider‐Hohendorf, Eric Baetscher, Evan L. Riddle, Marie Deffner, Emily Katsnelson, Janine Ferrant‐Orgettas, Julie Czerkowicz, John Anderson, Susan E. Goelz, Nicholas Schwab   +10 more
wiley   +1 more source

BioAgents: Bridging the gap in bioinformatics analysis with multi-agent systems. [PDF]

Sci Rep
Mehandru N, Hall AK, Melnichenko O, Dubinina Y, Tsirulnikov D, Bamman D, Alaa A, Saponas S, Malladi VS.   +8 more
europepmc   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

ReadSeeker: A DNABERT based de-novo read-level gene predictor. [PDF]

PLoS One
Wulf B, Dabrowski PW.
europepmc   +1 more source

Comparative Genomics Reveals the Regulatory Complexity of Bifidobacterial Arabinose and Arabino-Oligosaccharide Utilization

, 2018
Aleksandr A. Arzamasov, Douwe van Sinderen, Dmitry A. Rodionov   +2 more
openalex   +1 more source