Results 111 to 120 of about 9,641,170 (252)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Factors affecting the genotype × environment interaction in spring triticale grown in a Mediterranean environment

, 2001
The identification of the genotypic and environmental factors responsible for the genotype by environment interaction is essential in any breeding program.
Deidda, Mauro, Motzo, Rosella, Giunta, Francesco   +2 more
core  

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Genotype x environment interaction in cassava multi-environment trials via analytic factor.

PLoS ONE
The variability in genetic variance and covariance due to genotype × environment interaction (G×E) can hinder genotype selection accuracy, especially for complex traits.
Juraci Souza Sampaio Filho, Isadora Cristina Martins Oliveira, Maria Marta Pastina, Marcos de Souza Campos, Eder Jorge de Oliveira   +4 more
doaj   +1 more source

Genotype-environment interaction and sociology: Contributions and complexities

Genotype-environment interaction (GxE) refers to situations in which genetic effects connected to a phenotype are dependent upon variability in the environment, or when genes modify an organism's sensitivity to particular environmental features.
Avison, William R., Seabrook, Jamie A.
core  

Genotype-Year interaction ANOVA for fresh yield studied during three years.

Genotype-Year interaction ANOVA for fresh yield studied during three years.
Md. Ashraful Alam (7434188), Md. Atikur Rahman (13955704), Md. Riazul Islam (6270136), Ahmed Gaber (11917619), Srabanti Roy (14948968), Md. Mushfiqur Rahman (7382468), Md. Rafiqul Islam (403453), Akbar Hossain (12009419), Md. Marufur Rahman (14948962), Abu Jafor Obaidullah (17817288), Riyadh S. Almalki (17817294), Md. Nasirul Farid (17817291), Shailendra Nath Mozumder (14948971)   +12 more
core   +1 more source

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

Advanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song, Peilin Han, Jiaming Li, Xiaolong Li, Xiang Zhang, Jing Fan, Dongliang Liu, Jianfa Cai, Lingchao Zhang, Jun Wu   +9 more
wiley   +1 more source

Efficiency of Factor Analysis-Based Selection Indices Under Varying Heritability and Trait-Environment Correlations

Agriculture
The main approach for improving multiple traits simultaneously is the selection index. The most widely used selection indices are those based on factor analysis, which overcome statistical limitations such as multicollinearity and the reliance on ...
Wanessa Alves Lima Paiva, Brenda Vieira de Oliveira, Camila Ferreira Azevedo, Ana Carolina Campana Nascimento, Diego Jarquin, Moyses Nascimento   +5 more
doaj   +1 more source

Statistical Genetic Approaches to Investigate Genotype-by-Environment Interaction: Review and Novel Extension of Models [PDF]

Statistical genetic models of genotype-by-environment (G×E) interaction can be divided into two general classes, one on G×E interaction in response to dichotomous environments (e.g., sex, disease-affection status, or presence/absence of an exposure) and ...
Sarah Williams-Blangero, Diego, Vincent P., David Ortiz, Marcio Almeida, Eron G. Manusov, Vincent P. Diego, Sandra Laston, Laston, Sandra, Ortiz, David, Manusov, Eron G., John Blangero, Blangero, John, Williams-Blangero, Sarah, Almeida, Marcio   +13 more
core   +1 more source

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source