Results 231 to 240 of about 9,641,170 (252)

scH16S‐Seq Maps Klebsiella pneumoniae‐Associated Myeloid States and Reveals a CD38–NAD Immunometabolic Axis That Impairs Lysosomal Acidification in Sepsis

open access: yesAdvanced Science, EarlyView.
Single‐cell host–bacterial 16S co‐sequencing (scH16S‐seq) integrates cell‐associated bacterial 16S‐derived signals with host transcriptomes to resolve bacterial signal‐enriched myeloid states in Klebsiella pneumoniae sepsis. Complementary pharmacological and genetic analyses define a CD38–NAD immunometabolic axis connecting mitochondrial bioenergetic ...
Yangguang Li   +15 more
wiley   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

open access: yesAdvanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng   +17 more
wiley   +1 more source

Effect of Genotype × Environment Interaction on Yield of Maize Hybrids in Greece Using AMMI Analysis

Agronomy, 2021
George Katsaros   +2 more
exaly  

No Gene-Environment Interactions Found in Million Women Study of Breast Cancer

Ca-A Cancer Journal for Clinicians, 2010
John Henry Dreyfuss
exaly  

Human Papillomavirus Genotype Distributions Inform Screening and Vaccination Policy

Ca-A Cancer Journal for Clinicians, 2009
Mary Desmond Pinkowish, M D Pinkowish
exaly  

Genotype by Environment Interactions Across Diverse Rainfed Lowland Rice Environments

Field Crops Research, 1999
Joel Siopongco, L J Wade, S Sarkarung
exaly  

A Genomic Bias for Genotype–Environment Interactions in C. Elegans

Molecular Systems Biology, 2012
Craig P Hunter   +2 more
exaly  

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