Results 181 to 190 of about 26,046,977 (327)

Heart inflammation and piscine orthoreovirus genotype-1 in Pacific Canada Atlantic salmon net-pen farms: 2016-2019. [PDF]

BMC Vet Res, 2022
Polinski MP, Gross LA, Marty GD, Garver KA.   +3 more
europepmc   +1 more source

Systematic review with meta‐analysis: effectiveness and tolerability of interferon‐free direct‐acting antiviral regimens for chronic hepatitis C genotype 1 in routine clinical practice in Asia

Alimentary Pharmacology and Therapeutics, 2018
F. Ji, F. Ji, Bin Wei, Y. Yeo, E. Ogawa, E. Ogawa, B. Zou, C. Stave, Zongfang Li, S. Dang, N. Furusyo, R. Cheung, M. Nguyen   +12 more
semanticscholar   +1 more source

Cancer Cells Traverse Faster in Confined Space by Modifying Vimentin filaments With Nuclear Deformation and Promoting the Growth of Desired Tumor Spheroids

Advanced Materials Interfaces, EarlyView.
This study demonstrates how the Vimentin intermediate (VIM) filaments distribution/density regulates the attainment of different migration modes through cytoskeleton rearrangement and controls the nuclear morphology in migrating cells under physical confinement, which facilitates the faster traversing of those cells and the growth of post‐migration ...
Md Kowsar Alam, Jiao Zhai, Heng Zou, Yu Chen, Michael Yang   +4 more
wiley   +1 more source

Collision‐Resilient Winged Drones Enabled by Tensegrity Structures

Advanced Robotics Research, EarlyView.
Based on structures of birds such as the woodpeck, this article presents the collision‐resilient aerial robot, SWIFT. SWIFT leverages tensegrity structures in the fuselage and wings which allow it to undergo large deformations in a crash, without sustaining damage. Experiments show that SWIFT can reduce impact forces by 70% over conventional structures.
Omar Aloui, Raphael Zufferey, William Stewart, Mohammad Askari, Simon Jeger, Dario Floreano   +5 more
wiley   +1 more source

Retrospective multicentre study on the effectiveness of first-line direct-acting antivirals against hepatitis C virus genotype-1. [PDF]

J Clin Pharm Ther, 2022
Kaya M, Nakamura K, Sugiyama K, Kinae A, Yamaguchi H, Ukita H, Odagiri K, Ujiie C, Kato J, Kageyama F, Nagura M, Matsushita K, Sugiue K, Ishida H, Endo S, Suzuki T.   +15 more
europepmc   +1 more source

HA-1(H) Genotype Positive [PDF]

, 2020
openaire   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

Two mutations in the ORF1 of genotype 1 hepatitis E virus enhance virus replication and may associate with fulminant hepatic failure. [PDF]

Proc Natl Acad Sci U S A, 2022
Wang B, Tian D, Sooryanarain H, Mahsoub HM, Heffron CL, Hassebroek AM, Meng XJ.   +6 more
europepmc   +1 more source

Sofosbuvir‐velpatasvir‐voxilaprevir with or without ribavirin in direct‐acting antiviral–experienced patients with genotype 1 hepatitis C virus

Hepatology, 2017
E. Lawitz, F. Poordad, J. Wells, R. Hyland, Yin Yang, H. Dvory‐Sobol, L. Stamm, D. Brainard, J. Mchutchison, Carmen E. Landaverde, J. Gutierrez   +10 more
semanticscholar   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source