Results 181 to 190 of about 131,008 (302)

Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants

Advanced Science, EarlyView.
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei, Kai Zhang, Shuke Deng, Jinjie Chen, Xiaomei Huang, Jingfei Guo, Yuqing Wu, Yingjie Guo, Zhen Liang   +8 more
wiley   +1 more source

Genotype-by-environment interaction with high-dimensional environmental data: an example in pigs. [PDF]

Genet Sel Evol
Bussiman F, Lourenco D, Hidalgo J, Chen CY, Holl J, Misztal I, Vitezica ZG.   +6 more
europepmc   +1 more source

A simulation-based assessment of the efficiency of QTL mapping under environment and genotype x environment interaction effects. [PDF]

PLoS One, 2023
David GS, Viana JMS, das Graças Dias KO.   +2 more
europepmc   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Genotype by environment interaction analysis for seed cotton yield stability under normal irrigation and drought stress conditions using numerical stability statistics. [PDF]

Sci Rep
Yehia WMB, El-Hashash EF, El-Absy KM, Mesbah HA.   +3 more
europepmc   +1 more source

Genotype–environment interaction in antisocial behaviour [PDF]

Psychological Medicine, 1982
openaire   +2 more sources

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

Advanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong   +6 more
wiley   +1 more source

Genotype-by-environment interaction influencing sensory attributes and biochemical components of peanuts from China. [PDF]

Front Plant Sci
Tang Y, Cao S, Zhang C, Hu W, Zhou H, Wang M, Zhu L, Chen J, Zhang J, Zhang J.   +9 more
europepmc   +1 more source

Partitioning the forms of genotype-by-environment interaction in the reaction norm analysis of stability. [PDF]

Theor Appl Genet, 2023
Waters DL, van der Werf JHJ, Robinson H, Hickey LT, Clark SA.   +4 more
europepmc   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source