Results 201 to 210 of about 1,007,160 (300)

Identification, Virulence, and Molecular Characterization of a Recombinant Isolate of Grass Carp Reovirus Genotype I. [PDF]

Viruses, 2021
Zeng W, Bergmannc SM, Dong H, Yang Y, Wu M, Liu H, Chen Y, Li H.   +7 more
europepmc   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Establishment of a Triplex qPCR Assay for Differentiating Highly Virulent Genotype I Recombinant Virus From Low-Virulence Genotype I and Genotype II African Swine Fever Viruses Circulating in China. [PDF]

Transbound Emerg Dis
Ding L, Ren T, Bing G, Wang Z, Wang B, Ni J, Liu Y, Zhao R, Zhu Y, Li F, Liu R, Fu Q, Tian Z, Bu Z, Sun E, Zhao D.   +15 more
europepmc   +1 more source

Effectiveness of Live-Attenuated Genotype III Japanese Encephalitis Viral Vaccine against Circulating Genotype I Viruses in Swine. [PDF]

Viruses, 2022
Fan YC, Chen YY, Chen JM, Huang C, Huang M, Chiou SS.   +5 more
europepmc   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

Advanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao, Jennifer Michel, Eline Lorer, Markus Weinmann, Jacques Le Gouis, Claire Léon, Sibille Perrochon, David Alvarez, Vincent Leemans, Iñaki Balanzategui Guijarro, Jordi Moya Laraño, Sara Sánchez Moreno, Symanczik Sarah, Waibel Matthias, Hervé Vanderschuren, Cécile Thonar, Pierre Delaplace, Dominique Van Der Straeten   +17 more
wiley   +1 more source

Detection of African Swine Fever Virus Genotype II in West Africa (2020) and Its Co-Circulation With Endemic Genotype I: Implications for Pig Production. [PDF]

Transbound Emerg Dis
Meki IK, Adedeji AJ, Ouoba LB, Koffi YM, Diakité A, Settypalli TBK, Habibata-Zerbo L, Kouakou KV, Diakité MA, Masembe C, Sidi M, Douyeri TO, Dembelé F, Luka HE, Hamidou-Ouandaogo S, Dembelé C, Weka R, Bazimo G, Dakouo M, Olubade TA, Guitti-Kindo M, Traoré C, Gamra O, Guigma D, Sidibé CAK, Hambolu DA, Adama DD, Maïga BMDA, Ogunleye MA, Toluhi A, Maurice N, Couacy-Hymann E, Luka PD, Cattoli G, Lamien CE.   +34 more
europepmc   +1 more source

Association of Single-Nucleotide Polymorphisms in the VDR Gene with Tuberculosis and Infection of Beijing Genotype Mycobacterium tuberculosis. [PDF]

Infect Drug Resist, 2023
Yu J, Liu M, Mijiti X, Liu H, Wang Q, Yin C, Anwaierjiang A, Xu M, Li M, Deng L, Xiao H, Zhao X, Wan K, Li G, Yuan X.   +14 more
europepmc   +1 more source

The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo

Advanced Science, EarlyView.
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge, María Pagnon de la Vega, Silvia Zampar, Enrica Cerilli, Srinivas Koutarapu, Ling Wu, Paul Fraser, Sertan Arkan, Vilmantas Giedraitis, Lars Lannfelt, Greta Hultqvist, Stina Syvänen, Martin Ingelsson, Jörg Hanrieder, Dag Sehlin   +14 more
wiley   +1 more source

Predominance of Dengue Virus Serotype-1/Genotype-I in Eastern and Southeastern Ethiopia. [PDF]

Viruses
Tsegaye MM, Mekonnen AT, Gebretsion DT, Gelanew T, Alemayehu DH, Tefera DA, Woldemichael TS, Getaneh BA, Abera EK, Jebessa GG, Korkiso AK, Tessema MB, Asfaw AA, Temre YA, Wossen M, Piantadosi A, Zhu H, Abdissa A, Mihret A, Mulu A.   +19 more
europepmc   +1 more source

Genome analysis of clinical genotype Vibrio vulnificus isolated from seafood in Mangaluru Coast, India provides insights into its pathogenicity. [PDF]

Vet Q, 2023
Prithvisagar KS, Gollapalli P, D'Souza C, Rai P, Karunasagar I, Karunasagar I, Ballamoole KK.   +6 more
europepmc   +1 more source