Results 71 to 80 of about 14,985,405 (291)
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang +7 more
wiley +1 more source
Genotype x environment interaction on post-weaning performance and carcass in beef cattle
We analyzed average daily gain from weaning to yearling (ADG), yearling weight (YW), rib eye area, and subcutaneous fat thickness of 91 Angus, Hereford, Caracu, and Nellore cattle, and their crosses.
Leandro Lunardini Cardoso +2 more
doaj +1 more source
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García +13 more
wiley +1 more source
Genotype-environment-attribute interaction in an advanced cashew population through joint biplot graphical analysis. [PDF]
This this study investigated genotype x environment x attribute interaction in cashew trees using principal component analysis with multiple data ...
MOURA, C. F. H. +7 more
core +1 more source
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang +18 more
wiley +1 more source
The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun +27 more
wiley +1 more source
PHENOTYPIC STABILITY FOR SEED YIELD IN TARAMIRA
Genotype x environment interactions investigated for seed yield in taramira (Eruca sativa L.) during winter seasons over three years revealed significant variation for genotypes and genotype x environment interaction for seed yield.
A. HENRY and H.S. DAULAY
doaj +1 more source
The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo +20 more
wiley +1 more source
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source
Genotype x Environment interaction for quality traits in durum wheat cultivars adapted to different environments [PDF]
The quality traits of durum wheat are important for the utilization by the industries. These traits may be influenced by genotype and interaction of genotype and environment (GxE).
Kamar, M +7 more
core +1 more source

