Results 151 to 160 of about 243,271 (342)

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

Advanced Science, EarlyView.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu, Yueyin Han, Bingbing Xie, Lili Zhu, Wenxiu Xu, Yinzhen Han, Yue Liao, Shuwei Gao, Dingyuan Jiang, Jing Geng, Zhen Li, Yinan Hu, Huaping Dai   +12 more
wiley   +1 more source

Genotype x environment interaction and stability in promising elite clones of yield potentiality in respect to cane and sugar yield [PDF]

, 2020
N.R. Koli, Hitesh Kumar Koli, RK Soni, Arif Mohammad, B. L. Meena   +4 more
openalex   +1 more source

Environmental stratification based on a 28 x 28 diallel of open-pollinated maize varieties. [PDF]

, 2018
The objective of this study was to assess the representativeness of the test environments used by the maize breeding program of Embrapa in the first phase of genotype evaluation.
CARVALHO, H. W. L. de, GAMA, E. E. G. e, GUIMARAES, P. E. de O., MEIRELLES, W. F., PACHECO, C. A. P., PARENTONI, S. N., SANTOS, M. X. dos, SCAPIM, C. A., SILVA, H. D., VIEIRA JUNIOR, P. A.   +9 more
core  

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

Advanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu, Weize Xu, Da Lin, Leqiang Sun, Jinxia Dai, Gang Cao   +5 more
wiley   +1 more source

Genotype x environment interactions in pig breeding programmes

A pig breeding programme generally consists of different levels in a pyramidal structure, indicated as nucleus, multiplication and commercial level. Selection takes place at all levels but improvements generated in the nucleus determine eventually the rate of annual genetic change.
openaire   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Research Article Genotype x environment interaction for morpho-agronomic traits and color parameters in cassava in the Central Amazon

, 2022
E.I. Costa, César Augusto Ticona-Benavente, D.F. da Silva Filho   +2 more
openalex   +1 more source

GENOTYPE x ENVIRONMENT INTERACTIONS [PDF]

Annales de Génétique et de Sélection Animale, 1972
openaire   +1 more source

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source