Results 81 to 90 of about 55,163 (272)

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

Karakteristik Tapak, Benih Dan Bibit 11 Populasi Jabon Putih (Anthocepalus Cadamba Miq.) [PDF]

, 2014
White jabon (Anthocephalus cadamba Miq.) is a potential fast-growing tree species which naturally distributed in most of Indonesia islands. The study aims to assess the characteristic of site and morphophysiological variation of seeds and seedlings of ...
Bramasto, Y. (Yulianti), Siregar, I. Z. (Iskandar), Sudrajat, D. J. (Dede)   +2 more
core   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Genetic variability and character association studies in curry leaf ( Murraya koenigii)

Electronic Journal of Plant Breeding, 2020
Studies on variability and association of characters in curry leaf genotypes were carried out with eight genotypes collected around Coimbatore district at HC&RI, Coimbatore during 2017-2019.
N. Shoba, S. Balakrishnan, P. Paramaguru and K. Vithya
doaj   +1 more source

Assessment of genetic variation in selected germplasm of white jute (Corchorus capsularis L.) [PDF]

, 2016
Fifty-one genotypes of white jute from different geographic origins were evaluated to study their genetic variability with 11 morphological characters. Significant variation was observed among the genotypes for all the characters. Multivariate techniques
Alam, M. J., Ferdous, Jannatul, Islam, Md. Monirul, Pramanik, Md. Enayet Ali   +3 more
core  

Genomic selection in rubber tree breeding: A comparison of models and methods for managing G×E interactions [PDF]

, 2019
Several genomic prediction models combining genotype × environment (G×E) interactions have recently been developed and used for genomic selection (GS) in plant breeding programs. G×E interactions reduce selection accuracy and limit genetic gains in plant
Francisco, Felipe O., Fritsche-Neto, Roberto, Gonçalves, Paulo De Souza, Le Guen, Vincent, Scaloppi Junior, Erivaldo José, Souza, Anete Pereira, Souza, Livia Moura   +6 more
core   +2 more sources

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Cultivar diversity as a means of ecologically intensifying dry matter production in a perennial forage stand [PDF]

, 2014
The relationship between genotypic diversity and productivity has not been adequately explored in perennial forage production systems despite strong theoretical and empirical evidence supporting diversity\u27s role in ecosystem functioning in other ...
Pollnac, F. W., Smith, Richard G., Warren, Nicholas D.   +2 more
core   +2 more sources

Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair

Advanced Science, EarlyView.
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz, Luana C. Soares, Gretchen Greene, Fernando Messore, Mohammed Abuelem, Mingyu Li, Caroline Andersen, Mirriam Domocos, Elisa Vitiello, Rabeah Abdul Razak, Marlene Lawston, Gabriel Moser, Talia Vasaturo‐Kolodner, Mona Barkat, Roslyn M. Bill, Edward Mann, Linna Zhou, Mootaz M. Salman, Hagan Bayley, Zoltán Molnár, Francis G. Szele   +20 more
wiley   +1 more source

Genetic variability and character association studies in French bean (Phaseolus vulgaris) in Nilgiri hills of Tamil Nadu

The Indian Journal of Agricultural Sciences, 2019
In the present investigation, the genotypic and phenotypic coefficients of variation, heritability, correlation and path coefficient analysis were worked out for yield and its contributing characters of 77 French bean (Phaseolus vulgaris L) genotypes at ...
KOHIMA NOOPUR, M JAWAHARLAL, S PRANEETHA, POONAM KASHYAP, E SOMASUNDARAM   +4 more
doaj   +1 more source