Results 81 to 90 of about 55,860 (249)

Collision‐Resilient Winged Drones Enabled by Tensegrity Structures

Advanced Robotics Research, EarlyView.
Based on structures of birds such as the woodpeck, this article presents the collision‐resilient aerial robot, SWIFT. SWIFT leverages tensegrity structures in the fuselage and wings which allow it to undergo large deformations in a crash, without sustaining damage. Experiments show that SWIFT can reduce impact forces by 70% over conventional structures.
Omar Aloui, Raphael Zufferey, William Stewart, Mohammad Askari, Simon Jeger, Dario Floreano   +5 more
wiley   +1 more source

Interplay between pleiotropy and secondary selection determines rise and fall of mutators in stress response [PDF]

, 2009
Dramatic rise of mutators has been found to accompany adaptation of bacteria in response to many kinds of stress. Two views on the evolutionary origin of this phenomenon emerged: the pleiotropic hypothesis positing that it is a byproduct of environmental
A Giraud, A Sali, AC Shaver, B Li, CS Wylie, DK Klimov, E Dekel, E Denamur, E Denamur, E Shakhnovich, E Shakhnovich, EI Shakhnovich, EI Shakhnovich, EJ Deeds, ES Slechta, Eugene I. Shakhnovich, F Taddei, G Feng, GM Suel, HC Tsui, I Bjedov, I Matic, IN Berezovsky, JAGM de Visser, JB Andre, JD Bloom, JM Raser, JW Drake, KB Zeldovich, KB Zeldovich, KB Zeldovich, KK Yan, KL Huisinga, KP Bjornson, L Lopez-Maury, M Heo, M Wrande, MB Elowitz, MJ Schofield, ML Mendillo, Muyoung Heo, N Rosenfeld, O Tenaillon, O Tenaillon, PD Sniegowski, PD Sniegowski, PJ Gerrish, PL Foster, R Du, RE Lenski, RR Iyer, RS Galhardo, RS Harris, Rustom Antia, S Maslov, S Miyazawa, WA Rosche, WJ Blake   +57 more
core   +5 more sources

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

Genome-wide co-expression analysis in multiple tissues [PDF]

, 2008
Expression quantitative trait loci (eQTLs) represent genetic control points of gene expression, and can be categorized as cis- and trans-acting, reflecting local and distant regulation of gene expression respectively.
Aitman, T.J., Cook, S.A., Dickens, N.J., Grieve, I.C., Hubner, N., Kren, V., Mangion, J., Petretto, E., Pravenec, M.   +8 more
core   +7 more sources

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source

Genetic variability and character association studies in curry leaf ( Murraya koenigii)

Electronic Journal of Plant Breeding, 2020
Studies on variability and association of characters in curry leaf genotypes were carried out with eight genotypes collected around Coimbatore district at HC&RI, Coimbatore during 2017-2019.
N. Shoba, S. Balakrishnan, P. Paramaguru and K. Vithya
doaj   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Genetic variability and character association studies in French bean (Phaseolus vulgaris) in Nilgiri hills of Tamil Nadu

The Indian Journal of Agricultural Sciences, 2019
In the present investigation, the genotypic and phenotypic coefficients of variation, heritability, correlation and path coefficient analysis were worked out for yield and its contributing characters of 77 French bean (Phaseolus vulgaris L) genotypes at ...
KOHIMA NOOPUR, M JAWAHARLAL, S PRANEETHA, POONAM KASHYAP, E SOMASUNDARAM   +4 more
doaj   +1 more source

Possibilities and limitations of vegetative propagation in breeding and mass propagation of Norway spruce [PDF]

, 2003
The use of vegetative mass propagation in practical forestry with Norway spruce (Picea abies (L.) Karst.) is limited at present, although its potential to deliver high genetic gains is obvious.
Högberg, Karl-Anders
core