Results 221 to 230 of about 131,669 (291)

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

Advanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi, Song Wang, Yuqing Yan, Wei Chen, Yingying Cao, Dafan Chen, Wei Chen, Caiyun Ma, Xinjian Wan   +8 more
wiley   +1 more source

Chronic Chikungunya Arthritis in Northeastern Brazil: An Association with Very Severe Joint Pain and Lack of Correlation with <i>IL-6</i> and <i>TNFα</i> Gene Polymorphisms. [PDF]

Viruses
Maciel MSC, Martins CDB, Dos Santos AGM, Oliveira CN, Fernandes HF, Rodrigues RO, Yaochite JNU.   +6 more
europepmc   +1 more source

Notch2 Directs aTreg Cell Fate toward Immunoregulation or Inflammatory Pyroptosis

Advanced Science, EarlyView.
Schematic illustration showing that the Notch2 intracellular domain (NICD2) facilitates pyroptosis resistance in activated Tregs through the RREB1/Foxo1 signaling pathway. In addition, Notch2‐mediated pyroptosis resistance in activated Tregs promotes immunoregulatory capacity, thereby attenuating Th2‐driven inflammatory responses in allergic rhinitis ...
Yue‐Long Qiao, Shan Xu, You Zou, Rui Yang, Han Zheng, Jia‐Yu Liu, Hui‐Ming Fan, Yuan‐Yuan Zhang, Yong‐Gang Kong, Wo‐Er Jiao, Shi‐Ming Chen   +10 more
wiley   +1 more source

Identification of genetic markers associated with coronary artery disease in Pakistani Pashtun population: A case-control association study. [PDF]

Medicine (Baltimore)
Jan A, Ullah A, Khattak M, Shah WA, Akbar R, Nahla UA.   +5 more
europepmc   +1 more source

Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits

Advanced Science, EarlyView.
Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu, Shiyu Huang, Jie Wang, Tian Wang, Qingqing Han, Kexin Wu, Zhen Gao, Xiaolei Shi, Tianli Tu, Ming Wang, Laimei Huang, Jiaomei Chen, Yunqi Liu, Yumei Zhang, Guoqiang Lin, Zhichang Chen, Xu Chen   +16 more
wiley   +1 more source

Multivariate stability analysis to select elite rice (Oryza sativa L.) genotypes for grain yield, zinc and Iron. [PDF]

Sci Rep
Singh A, Singh DK, Singh SK, Singh VK, Kumar A.   +4 more
europepmc   +1 more source

Inheritance and Selection of Quantitative Characters in Burley Tobacco. : II. Heritability and Genotypic Correlation in F<SUB>2</SUB>∼F<SUB>4</SUB> Generations of a Varietal Cross, Burley 1 x Harmony

, 1971
T. Oinuma
openalex   +2 more sources

Correlation between phenotypic and genotypic drug resistance to kanamycin and amikacin in clinical isolates of Mycobacterium tuberculosis

, 2020
Azam Ahmadi, Maryam Sadrnia, Mohammad Arjomandzadegan, Leonid Titov   +3 more
openalex   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source