Results 251 to 260 of about 131,669 (291)
Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu +13 more
wiley +1 more source
Role of Leaf Traits in Driving Genotypic Diversity-Mediated Associational Effects in Silver Birch. [PDF]
Felix JA, Stevenson PC, Koricheva J.
europepmc +1 more source
Comment on “De Novo Reconstruction of 3D Human Facial Images from DNA Sequence”
This comment examines AI‐driven DNA‐based facial reconstruction, focusing on the Difface model. While such technologies promise biomedical and forensic applications, they pose significant ethical, legal, and methodological challenges. We emphasize transparency, benchmarking, and rigorous validation to avoid misinterpretation and misuse.
Jennifer K. Wagner +3 more
wiley +1 more source
A Logratio Approach to the Analysis of Autosomal Genotype Frequencies Across Multiple Samples. [PDF]
Graffelman J.
europepmc +1 more source
Study the estimates of correlation coefficient for genotypic level among different character’s and correlation between yield and yield contributing traits in tuberose [PDF]
Mohit Chaudhary +5 more
openalex
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen +12 more
wiley +1 more source

