Results 261 to 270 of about 783,438 (323)

Genotyping analysis of over 130,000 CIMMYT bread wheat breeding lines: A decade-long effort in optimizing wheat genotyping. [PDF]

Plant Genome
Shrestha S, Adhikari L, Crain J, Dreisigacker S, Wu S, Singh RP, Mondal S, Juliana P, Crossa J, Lucas M, Elbasyoni I, Poland J.   +11 more
europepmc   +1 more source

Genotyping [PDF]

, 2020
openaire   +1 more source

Efficacy and safety of the Russian protease inhibitor narlaprevir at treatment-naive and earlier treated noncirrhotic patients with the 1st genotype chronic hepatitis C (PIONEER study)

, 2018
М. В. Маевская, В. Т. Ивашкин, О О Знойко, Е. А. Климова, Dzhamal Abdurakhmanov, И. Г. Бакулин, Pavel Bogomolov, Э З Бурневич, М. Ю. Галушко, Н. И. Гейвандова, К. В. Жданов, Е. В. Эсауленко, Svetlana Kizhlo, Д. Ю. Константинов, Н. И. Миронова, В. Г. Морозов, E. Strebkova, И. Г. Никитин, М. Ф. Осипенко, В. Д. Пасечников, Olga Sagalova, И. М. Хаертынова, Vladimir Chulanov, А. А. Яковлев, И. А. Васютин, E.P. Tarkhova, Emilia N. Krasavina, M. Samsonov   +27 more
openalex   +2 more sources

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Impact of CYP2C19 point-of-care testing on the clinical outcome in patients receiving personalized clopidogrel therapy: systemic review and meta-analysis. [PDF]

Front Pharmacol
Mohammed S, Ali Z, Mohammed N, El-Menyar A, Al Suwaidi J, Al-Hail M, Al-Muftah W, Abdel-Latif R, Sim MS.   +8 more
europepmc   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Design and Evaluation of Next-Generation HIV Genotyping for Detection of Resistance Mutations to 28 Antiretroviral Drugs Across 5 Major Classes Including Lenacapavir. [PDF]

Clin Infect Dis
Park SY, Takayama C, Ryu J, Sattah M, Badii Z, Kim JW, Shafer RW, Gorbach PM, Lee HY.   +8 more
europepmc   +1 more source

Genotyping of composite germplasm set, Tier 1, Musa (SP1) [PDF]

, 2007
Hippolyte, Isabelle, Kolesnikova-Allen, Maria, Perrier, Xavier, Rouard, Mathieu, Roux, Nicolas   +4 more
core  

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source