Results 261 to 270 of about 782,061 (323)

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

Advanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li, Bao Dong, Zheng‐Lin Ren, Xue‐Guang Zhu, Quan Lei, Yoonseong Park, Jin‐Jun Wang, Hong‐Bo Jiang   +7 more
wiley   +1 more source

Editorial: Precision medicine: recent advances, current challenges and future perspectives

Frontiers in Pharmacology
Oriana Awwad, Mamoun Ahram, Francesca Coperchini, Mariam Abdel Jalil   +3 more
doaj   +1 more source

TEvarSim: A genome simulator for transposable element (TE) variants. [PDF]

PLoS Comput Biol
Miao J, Li D.
europepmc   +1 more source

SILICON AND THIOUREA MEDIATED STIMULATION OF SALT TOLERANCE VARYING BETWEEN THREE FODDER BEET (BETA VULGARIS L.) GENOTYPES

, 2019
Akbar Ali
openalex   +1 more source

Irgm1 Improves Postinfarction Cardiac Repair by Promoting Neutrophil Clearance and Efferocytosis

Advanced Science, EarlyView.
The Irgm1‐PDIA3 axis enhances post‐infarction cardiac repair by accelerating neutrophil clearance and facilitating efferocytosis. Irgm1 holds potential as a prognostic biomarker in MI, and LOC14 may represent a therapeutic option to improve cardiac repair, especially in cases of Irgm1 deficiency.
Zeng Wang, Lai Wei, Mingyang Wang, Shanjie Wang, Lili Xiu, Jiaxiang Sun, Rongzhe Lu, Yige Liu, Jiaxin Wang, Fengyi Liu, Weike Liu, Bo Yu, Yong Sun, Xueqin Gao, Shaohong Fang   +14 more
wiley   +1 more source

Editorial: Editor’s feature: negative findings in pharmacogenetics and pharmacogenomics volume II

Frontiers in Pharmacology
José A. G. Agúndez, Elena García-Martín, Luis Abel Quiñones, Luis Abel Quiñones   +3 more
doaj   +1 more source

CtGAP 2.0: enhanced genome assembly, strain resolution, and phylogenomics for <i>Chlamydia trachomatis</i>. [PDF]

Microbiol Resour Announc
Olagoke O, Read TD, Dean D.
europepmc   +1 more source

Genotyping [PDF]

, 2020
openaire   +1 more source

UBE2T‐Driven p53 Degradation Rewires Glycolysis to Orchestrate Lactylation‐Mediated CAFs Activation and ECM Deposition in Pancreatic Cancer

Advanced Science, EarlyView.
This study integrates multi‐omics to reveal the critical role of UBE2T in driving malignancy and stromal co‐evolution in PDAC. UBE2T potentiates glycolysis by regulating p53 degradation via a positive feedback loop, thereby promoting histone H3 lysine 18 lactylation in CAFs and stromal deposition. The UBE2T inhibitor PGG represents a potential strategy
Yong Ma, Wenbo Liu, Mingdou Li, Tao Wang, Bin Zhao, Keshen Wang, Qichen He, Haonan Sun, Huiguo Qing, Xiaoying Guan, Wengui Shi, Long Qin, Yuman Dong, Huinian Zhou, Zeyuan Yu, Xiangyan Jiang, Zuoyi Jiao   +16 more
wiley   +1 more source

Genome-Wide Development and Validation of KASP-Based SNP Markers in <i>Neophocaena asiaeorientalis asiaeorientalis</i>. [PDF]

Animals (Basel)
Yin D, Zhang H, Tang M, Que J, Lin D, Ying C, Zhang J, Yu J, Liu K.   +8 more
europepmc   +1 more source