Results 301 to 310 of about 1,163,135 (344)

Podocyte RIPK3 Deletion Improves Diabetic Kidney Disease by Attenuating NF‐κB p65 Driven Inflammation

Advanced Science, EarlyView.
Prevention and treatment of diabetic kidney disease (DKD) have become a major global public health challenge. This study shed new light on the underlying pathogenic mechanisms of podocyte injury in DKD and highlights the therapeutic potential of mitigating podocyte injury through inhibition of the RIPK3/NF‐κB p65‐mediated inflammatory response as a ...
Lu'an Li, Jiaying Li, Ruizhao Li, Xingchen Zhao, Yuanhan Chen, Yating Cai, Yan Yang, Weiteng Wang, Siqi Zheng, Li Zhang, Xinling Liang   +10 more
wiley   +1 more source

Exon 11 Polymorphism (rs1126797) in the Thyroid Peroxidase (<i>TPO</i>) Gene Among Caucasian Polish Patients with Autoimmune Thyroiditis: A Short Communication. [PDF]

Int J Mol Sci
Lacka K, Maciejewski A, Łącka AM, Herman W, Lacki JK, Żaba R, Kowalczyk MJ.   +6 more
europepmc   +1 more source

A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain

Advanced Science, EarlyView.
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria, Cristina Iglesias, Sascha Jung, Javier Arcos Hodar, Ruben Nogueiras, Antonio del Sol   +5 more
wiley   +1 more source

Bone Marrow Aplasia and Neutropenic Fever Following Azathioprine Dose Escalation in a TPMT-Deficient Patient with Crohn's Disease and Psoriatic Arthritis-A CARE-Compliant Case. [PDF]

Clin Pract
Wroński K, Holecki MT, Boguszewska N, Skrzypczak-Zielińska M, Chudek JT.   +4 more
europepmc   +1 more source

The triage role of cytological DNA methylation in women with non-16/18, specifically genotyping high-risk HPV infection. [PDF]

Br J Cancer
Su H, Jin X, Kong L, You Y, Wu H, Liou Y, Li L.   +6 more
europepmc   +1 more source

Novel haplotypes of genetic polymorphisms in alcohol metabolizing enzymes in Kampala, Uganda. [PDF]

BMC Res Notes
Okwasiimire R, Baingana RK, Kasozi DM.
europepmc   +1 more source

DPYD Genotyping, Fluoropyrimidine Dosage and Toxicity: An Umbrella Review of Systematic Reviews. [PDF]

Pharmaceuticals (Basel)
Otero-Torres S, Rodríguez-Mauriz R, Fort-Casamartina E, Clopés-Estela A, Soler-Rotllant F, Fontanals-Martínez S, Montero-Pérez O.   +6 more
europepmc   +1 more source

Genome-wide association studies reveal genetic control of nutritional quality, milling traits, and agronomic characteristics in oat (Avena sativa L.). [PDF]

Plant Genome
Ardayfio NK, Kinney C, Li D, Naraghi SM, McMullen MS, Fiedler JD.   +5 more
europepmc   +1 more source