Results 321 to 330 of about 10,219,641 (384)

Proteomic Profiling of the Large‐Vessel Vasculitis Spectrum Identifying Shared Signatures of Innate Immune Activation and Stromal Remodeling

Arthritis &Rheumatology, EarlyView.
Objective Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large‐vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments. Methods Plasma proteomic profiling of 184 proteins was performed in two cohorts. Cohort 1 included
Robert T. Maughan, Erin Macdonald‐Dunlop, Lubna Haroon‐Rashid, Louise Sorensen, Natalie Chaddock, Shauna Masters, Andrew Porter, Marta Peverelli, Charis Pericleous, Andrew Hutchings, James Robinson, Taryn Youngstein, Raashid A. Luqmani, Justin C. Mason, Ann W. Morgan, James E. Peters   +15 more
wiley   +1 more source

Combining genotyping approaches improves resolution for association mapping: a case study in tropical maize under water stress conditions. [PDF]

Front Plant Sci
de Pontes FCF, Machado IP, Silveira MVS, Lobo ALA, Sabadin F, Fritsche-Neto R, DoVale JC.   +6 more
europepmc   +1 more source

Peripheral Biomarker Signatures in Rheumatoid Arthritis–Associated Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) is a significant cause of morbidity and mortality among patients with RA, yet effective risk stratification for RA‐ILD is lacking. We sought to characterize unique peripheral blood biomarker signatures in RA that could improve RA‐ILD discrimination beyond clinical and genetic ...
Austin M. Wheeler, Joshua F. Baker, Thomas R. Riley IV, Tate M. Johnson, Yangyuna Yang, Punyasha Roul, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Gail Kerr, Dana P. Ascherman, Paul Monach, Andreas Reimold, Scott Matson, Jill A. Poole, Michael J. Duryee, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +18 more
wiley   +1 more source

PCR-Based Genotyping of Zebrafish Genetic Mutants. [PDF]

Bio Protoc
Babu S, Nishiwaki Y, Masai I.
europepmc   +1 more source

Comparative Analysis of Phenotypic and Genotypic Differences Between Individuals Affected by Regressive and Non‐Regressive Autism: A Cross‐Sectional Study

Autism Research, EarlyView.
ABSTRACT Development among autistic youth varies widely. A subgroup of children experiences regression, defined as the loss of previously acquired developmental skills. Various genetic and environmental factors have been suggested as potential contributors.
Seyed Hassan Tonekaboni, Alana Iaboni, Brett Trost, Miriam Reuter, Zsuzsa Lindenmaier, Azadeh Kushki, Elizabeth Kelley, Jessica Jones, Muhammed Ayub, Stelios Georgiades, Robert Nicolson, Elim Chan, Andrada Cretu, Jessica Brian, Evdokia Anagnostou   +14 more
wiley   +1 more source

Using feedback in pooled experiments augmented with imputation for high genotyping accuracy at reduced cost. [PDF]

G3 (Bethesda)
Clouard C, Nettelblad C.
europepmc   +1 more source

review marcatori genetici acquacoltura [PDF]

, 2012
Guarniero, Ilaria
core  

Feasibility and population exposure of 5‐fluorouracil using therapeutic drug monitoring (PREDICT‐5FU): A multicentre clinical trial

British Journal of Clinical Pharmacology, EarlyView.
Aim PREDICT‐5FU aimed to document 5‐fluorouracil (5FU) exposure in a cancer population and to evaluate the feasibility of 5FU and capecitabine therapeutic drug monitoring (TDM) in patients receiving standard doses and schedules. Methods Multicentre, prospective, observational single‐arm study.
Sarah Glewis, Michael Michael, Howard Gurney, Ian Olver, Nicholas Zdenkowski, Stephen Ackland, Craig Kukard, Madawa Jayawardana, S. Sandun M. Silva, Marliese Alexander, Jeanne Tie, Peter Galettis, Jennifer H. Martin   +12 more
wiley   +1 more source

The importance of genotyping within the climate-smart plant breeding value chain - integrative tools for genetic enhancement programs. [PDF]

Front Plant Sci
Garcia-Oliveira AL, Ortiz R, Sarsu F, Rasmussen SK, Agre P, Asfaw A, Kante M, Chander S.   +7 more
europepmc   +1 more source

Safety and effectiveness of the anti‐amyloid monoclonal antibody (mAb) drug lecanemab for early Alzheimer's disease: The pharmacovigilance perspective

British Journal of Clinical Pharmacology, Volume 91, Issue 5, Page 1352-1360, May 2025.
Abstract The development of humanized IgG1 anti‐amyloid monoclonal antibodies, such as lecanemab, provides a promising novel treatment pathway with potential disease‐modifying effects for patients with early Alzheimer's disease (AD). Lecanemab, which gained marketing approval by the United States Food and Drug Administration (US FDA) in July 2023, has ...
Amy Bobbins, Miranda Davies, Elizabeth Lynn, Debabrata Roy, Alison Yeomans, Saad A. W. Shakir   +5 more
wiley   +1 more source