Results 331 to 340 of about 10,219,641 (384)

The feasibility of pharmacokinetic‐based dosing of hydroxyurea for children with sickle cell anaemia in Uganda: Baseline results of the alternative dosing and prevention of transfusions trial

British Journal of Clinical Pharmacology, EarlyView.
Abstract Pharmacokinetic (PK)‐guided dosing of hydroxyurea for children with sickle cell anaemia (SCA) could optimize dosing and improve outcomes, but its feasibility has not been demonstrated in low‐resource settings where the majority of affected children live.
Alexandra Power‐Hays, Ruth Namazzi, Min Dong, Caroline Kazinga, Charles Kato, Sadat Aliwuya, Kathryn McElhinney, Andrea L. Conroy, Adam Lane, Chandy John, Alexander A. Vinks, Teresa Latham, Robert O. Opoka, Russell E. Ware   +13 more
wiley   +1 more source

Genetic Epidemiology and Resistance Investigations of Clinical Yeasts in Alexandria, Egypt. [PDF]

Pathogens
Spruijtenburg B, Melchior do Prado C, Kempen MV, Shawky SM, Meis JF, Aparecida Vicente V, Queiroz-Telles F, Groot T, El-Kholy MA, Meijer EFJ.   +9 more
europepmc   +1 more source

Consideration of ethnic differences in approvals for anti‐HIV medicines in Japan: Evaluation based on pharmacokinetic studies and post‐marketing data

British Journal of Clinical Pharmacology, EarlyView.
More than 30 anti‐HIV drugs have been approved in Japan using data from dossiers submitted to the United States or European regulatory authorities since 1998. These drugs were approved with the same dosage and administration regimes as in the United States and Europe, using data from pivotal studies that rarely included any Japanese patients, whereas ...
Rumiko Shimazawa, Masayuki Ikeda
wiley   +1 more source

Identifying zoonotic risks: molecular insights into Cryptosporidium and Enterocytozoon bieneusi in pediatric cancer patients in Ahvaz, 2024. [PDF]

Parasitol Res
Makipour H, Haghighi A, Halakou A, Dayer D, Bitaraf S, Farhadi Kia A, Abbasi Nasab M, Mori M, Salehi Kahyesh R, Mirjalali H.   +9 more
europepmc   +1 more source

Non‐targeted metabolite profiling reveals biochemical diversity of three East Asian mosses

Bulletin of the Korean Chemical Society, EarlyView.
Mosses are known for their bioactive composition and adaptation to environmental stresses. This study explores the metabolic diversity of three East Asian moss species, Niphotrichum japonicum, Calohypnum plumiforme, and Polytrichum formosum, using high‐resolution mass spectrometry. Lipids, particularly unsaturated fatty acids linked to cold adaptation,
Fatima Tuz Zahra, Kyungwon Min, Jungeun Lee, Maeng‐Joon Jung, Hyoungseok Lee, Sunghwan Kim   +5 more
wiley   +1 more source

A combined risk model shows viability for personalized breast cancer risk assessment in the Indonesian population: A case/control study. [PDF]

PLoS One
Rabbani B, Tanu SG, Ramanto KN, Audrienna J, Fernandez EA, Aldila F, Gonzalez-Porta M, Valeska MD, Haruman J, Ulag LH, Maulana Y, Junusmin KI, Amelia M, Gabriella G, Soetyono F, Fajarrahman A, Hasan SSM, Agatha FA, Wijaya M, Br Sormin ST, Sani L, Irwanto A, Haryono SJ, Ali S.   +23 more
europepmc   +1 more source

Evaluating thermotolerant sunflower genotypes with temperature induction response (TIR) technique

V. Aparna, Lakshmi Prayaga, C. Sarada, Arti Guhe   +3 more
openalex   +2 more sources

Identification and validation of intergeneric hybrids between Saccharum officinarum and Erianthus rockii using molecular and cytogenetic tools. [PDF]

PLoS One
Wang G, Wang J, Zhang W, Xu H, Liang Q, Qin Y, Wu Q, Wu J, Fu C, Zhou F, An Y, Wang Q, Chang H.   +12 more
europepmc   +1 more source

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source