Results 201 to 210 of about 1,991,563 (339)

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

open access: yesAdvanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang   +11 more
wiley   +1 more source

Engineering Dimensional Configuration of Single‐Atom S‐Cu‐S Sites as Reversible Electron Station for Enhanced Peroxidase‐Mimicking

open access: yesAdvanced Science, EarlyView.
L‐cysteine triggers auto‐assembly of POD‐like 3D biomimetic S‐Cu‐S single‐atom nanozymes on MoS2 (MoCC). MoCC shows 16.3‐fold higher catalytic velocity and 17.9‐fold greater affinity than HRP, enabling efficient •OH generation via enhanced electron inversion and transfer.
Wenjie Ma   +12 more
wiley   +1 more source

Advancing Yeast Identification Using High-Throughput DNA Barcode Data From a Curated Culture Collection. [PDF]

open access: yesMol Ecol Resour
Vu D   +12 more
europepmc   +1 more source

Two Novel S‐methyltransferases Confer Dimethylsulfide Production in Actinomycetota

open access: yesAdvanced Science, EarlyView.
This study identifies two novel S‐adenosine‐methionine‐dependent methyltransferases, MddM1 and MddM2, in actinomycetes from the Mariana Trench. These enzymes can convert toxic hydrogen sulfide (H2S) and methanethiol (MeSH) into dimethylsulfide (DMS), serving as a cellular detoxification and oxidative stress response.
Ruihong Guo   +11 more
wiley   +1 more source

Metagenomic screening of the virome of symptomatic tomato plants from La Réunion Island uncovers a complex of viruses including a newly identified whitefly-transmitted polerovirus. [PDF]

open access: yesArch Virol
Lett JM   +13 more
europepmc   +1 more source

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