Results 261 to 270 of about 1,875,391 (327)

Discovery to Engineering of Mycotoxin Deoxynivalenol Degrading Enzymes Based on the Specialized Glyoxalase I

open access: yesAdvanced Science, EarlyView.
Deoxynivalenol (DON), a prevalent food mycotoxin, is an important risk factor in global food safety. A molecular phylogeny‐guided engineering approach is devised to repurpose specialized glyoxalase I (SPG) as a DON deactivator. Engineered SPG variants demonstrate superior stability and are highly capable of converting DON into less toxic products ...
Seung Hee Lee   +12 more
wiley   +1 more source

Protected Chaos in a Topological Lattice

open access: yesAdvanced Science, EarlyView.
Topological and chaotic dynamics are often considered incompatible, with one expected to dominate or disrupt the other. This work reveals that topological localization can persist even under strong chaotic dynamics and, counter‐intuitively, protect chaotic behavior.
Haydar Sahin   +6 more
wiley   +1 more source

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

open access: yesAdvanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen   +9 more
wiley   +1 more source

Phytophthora Disrupts Plant Immunity by Manipulating Nitric Oxide Homeostasis Through GSNOR Inhibition

open access: yesAdvanced Science, EarlyView.
Phytophthora capsici effector PcRD18 targets tomato GSNOR to disrupt NO homeostasis, promoting S‐nitrosylation of immune proteins like RBOHD. This suppresses ROS bursts and promotes pathogen infection. Mutation of the PcRD18‐binding sites of GSNOR avoids pathogen manipulation and offers a strategy to enhance crop resistance. Abstract Nitric oxide (NO),
Tingting Li   +8 more
wiley   +1 more source

Prompting Interfacial Elastic Instability for Effective and Durable Icephobic Surfaces

open access: yesAdvanced Science, EarlyView.
To address the inherent trade‐off between icephobicity and the mechanical strength of icephobic materials, a new icephobic material design strategy is proposed by integrating fibrous construction frameworks and icephobic polymer. The structure prompts interfacial elastic instability and the subsequent undulatory interfacial stress at ice/solid ...
Xinyu Fan   +5 more
wiley   +1 more source

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