Results 121 to 130 of about 69,023 (286)
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Preliminary geophysical interpretation of the McKeand River area, southern Baffin Island, Nunavut: insights from gravity, magnetic and geological data [PDF]
The recently completed McKeand River and Amittok Lake aeromagnetic surveys on southern Baffin Island, Nunavut pro- vide a new high-resolution magnetic dataset over an area with no previous coverage. Complemented by regional gravity data, newly acquired
St-Onge, Marc R. +2 more
core
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Tweeting in open public space : case study Belgrade [PDF]
Public spaces represent essential elements of vibrant, inclusive, and smart cities. Being attractive, safe, comfortable, active and sociable, open public spaces play the main role in revitalizing communities, supporting their sense of identity and ...
Dinkic, Nikola +3 more
core +1 more source
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
Ptarmigan Fiord basement-cover thrust imbricates, Baffin Island, Nunavut [PDF]
The rocks at Ptarmigan Fiord on the Hall Peninsula of Baffin Island underwent midcrustal deformation during the formation of the Paleoproterozoic Trans-Hudson Orogen.
Carr, S D +4 more
core
Atomic Size Misfit for Electrocatalytic Small Molecule Activation
This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong +3 more
wiley +1 more source
Completing the bedrock mapping of southern Baffin Island, Nunavut; plutonic suites and regional stratigraphy [PDF]
This paper summarizes the field observations and initial interpretations following eight weeks of regional and targeted bed- rock mapping on south-central Baffin Island, Nunavut.
Dyck, B J +4 more
core

