Results 91 to 100 of about 1,882,464 (376)

Observation of geo-neutrinos

open access: yesPhysics Letters B, 2010
Geo-neutrinos, electron anti-neutrinos produced in beta decays of naturally occurring radioactive isotopes in the Earth, are a unique direct probe of our planet's interior. We report the first observation at more than 3$ $ C.L. of geo-neutrinos, performed with the Borexino detector at Laboratori Nazionali del Gran Sasso.
Bellini, G.   +88 more
openaire   +5 more sources

Geo‐electromagnetic research aids geo‐hazard mitigation [PDF]

open access: yesEos, Transactions American Geophysical Union, 2002
Some 100 Earth scientists from nine different nations recently gathered in Lerici, Italy; for the Second International Workshop on Geo‐Electro‐Magnetism. While this was not a thematic meeting, most of the 40 papers presented focused on applications of electromagnetic methods to natural or man‐made hazards such as known faults, seismically active ...
M. Chiappini   +2 more
openaire   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

An integrated prognostic model of nuclear-encoded mitochondrial gene signature and clinical information for hepatocellular carcinoma

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To establish a prognostic model for the overall survival (OS) of hepatocellular carcinoma (HCC) based on mitochondrial genes and clinical information.Methods·The gene expression and the clinical data of 369 HCC patients and 50 controls with ...
Kedeerya Aishanjiang   +4 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

HOTAIR Facilitates Endocrine Resistance in Breast Cancer Through ESR1/miR-130b-3p Axis: Comprehensive Analysis of mRNA-miRNA-lncRNA Network

open access: yesInternational Journal of General Medicine, 2021
Mingdi Zhang, Kejin Wu, Peng Zhang, Yiran Qiu, Fang Bai, Hongliang Chen Department of Breast Surgery, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, People’s Republic of ChinaCorrespondence: Hongliang ChenDepartment of Breast Surgery ...
Zhang M   +5 more
doaj  

Estimating Ground‐Level PM2.5 by Fusing Satellite and Station Observations: A Geo‐Intelligent Deep Learning Approach [PDF]

open access: yes, 2017
Fusing satellite observations and station measurements to estimate ground‐level PM2.5 is promising for monitoring PM2.5 pollution. A geo‐intelligent approach, which incorporates geographical correlation into an intelligent deep learning architecture, is ...
Tongwen Li   +4 more
semanticscholar   +1 more source

Geo-questionnaire in urban planning – preliminary results of the experimental application in Poland [PDF]

open access: yes, 2016
Changes in the attitude of local authorities towards the public participation in the decision making processes have prompted development of new methods of such involvement.
Brudka, Cezary   +6 more
core   +1 more source

The first-order phase transition between dimerized-antiferromagnetic and uniform-antiferromagnetic phases in Cu_(1-x)M_xGeO_3

open access: yes, 1999
We have performed detailed magnetic susceptibility measurements as well as synchrotron x-ray diffraction studies to determine the temperature vs concentration ($T$ - $x$) phase diagram of Cu${}_{1-x}$Mg${}_x$GeO${}_3$.
H. Fukuyama   +24 more
core   +1 more source

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