Results 101 to 110 of about 1,882,464 (376)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Filantrocapitalismo digital en educación: Covid-19, UNESCO, Google, Facebook y Microsoft

open access: yesRevista Teknokultura, 2020
El propósito de este artículo es analizar nuevas formas de filantrocapitalismo digital en la política educativa a raíz de la pandemia Covid-19. El filantrocapitalismo digital es una hibridación conceptual que unifica principios del capitalismo digital ...
Geo Saura
doaj   +1 more source

LEGOStore: A Linearizable Geo-Distributed Store Combining Replication\n and Erasure Coding [PDF]

open access: green, 2021
Hamidreza Zare   +6 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Geografía e inteligencia territorial : Geo-grafein, Geo-explanans, Geo-transformare [PDF]

open access: yes, 2013
La Geografía y la Inteligencia Territorial pueden, juntas, ser una puerta a disciplinas y proyectos científicos mas encantadores, alegres y útiles en miles de millones de personas que no hacen Geografía, y que la conocen de otra forma, cuando no más crítica, más tradicional.
openaire   +3 more sources

The Homomorphism Poset of K_{2,n}

open access: yes, 2012
A geometric graph is a simple graph G together with a straight line drawing of G in the plane with the vertices in general position. Two geometric realizations of a simple graph are geo-isomorphic if there is a vertex bijection between them that ...
Cockburn, Sally, Song, Yonghyun
core  

Orbit to orbit transportation [PDF]

open access: yes, 1980
Orbital transfer vehicle propulsion options for SPS include both chemical (COTV) and electrical (EOTV) options. The proposed EOTV construction method is similar to that of the SPS and, by the addition of a transmitting antenna, may serve as a ...
Bergeron, R. P.
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

ADVANCEMENTS IN SATELLITE COMMUNICATION SYSTEMS: CHALLENGES AND OPPORTUNITIES [PDF]

open access: yesJournal of Mechanics of Continua and Mathematical Sciences
From its early days as a fledgling technology, satellite communication has come a long way to become a flourishing component of the global technological ecosystem that determines our increasingly interdependent world.
Basim Galeb   +4 more
doaj   +1 more source

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