Results 131 to 140 of about 1,882,464 (376)

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

The Geo-Cultural and Geo-Linguistic Dimension of Media [PDF]

open access: yesInternational Letters of Social and Humanistic Sciences, 2014
Besides the potential advancement of technology, the global and local communication is framing itself within bigger dimensions. The messages delivered by actual media means and the intensive exchange of experiences and ideas are conceived by the communication specialists as the most effective ways to configure the positions and therefore, are offering ...
openaire   +2 more sources

A Local-Global LDA Model for Discovering Geographical Topics from Social Media

open access: yes, 2016
Micro-blogging services can track users' geo-locations when users check-in their places or use geo-tagging which implicitly reveals locations. This "geo tracking" can help to find topics triggered by some events in certain regions.
Jin, Yaohui, Qiang, Siwei, Wang, Yongkun
core   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Bioinformatics Analysis and Validation Identify CDK1 and MAD2L1 as Prognostic Markers of Rhabdomyosarcoma

open access: yesCancer Management and Research, 2020
Suying Lu,1,2,* Chengtao Sun,3,* Huimou Chen,1,2,* Chao Zhang,1,4,* Wei Li,5 Liuhong Wu,1,2 Jia Zhu,1,2 Feifei Sun,1,2 Junting Huang,1,2 Juan Wang,1,2 Zijun Zhen,1,2 Ruiqing Cai,1,2 Xiaofei Sun,1,2 Yizhuo Zhang,1,2 Xing Zhang1,6 1State Key Laboratory of ...
Lu S   +14 more
doaj  

NCBI GEO: mining tens of millions of expression profiles—database and tools update

open access: yesNucleic Acids Res., 2006
The Gene Expression Omnibus (GEO) repository at the National Center for Biotechnology Information (NCBI) archives and freely disseminates microarray and other forms of high-throughput data generated by the scientific community. The database has a minimum
T. Barrett   +9 more
semanticscholar   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Cuproptosis-related genes are involved in immunodeficiency following ischemic stroke

open access: yesArchives of Medical Science
Introduction Accumulating studies have shown that copper has a detrimental effect in cells, and the cuproptosis-related gene signatures have been constructed as clinical tools to predict prognosis in tumors.
Jinshi Li   +4 more
doaj   +1 more source

Trading Timeliness and Accuracy in Geo-Distributed Streaming Analytics [PDF]

open access: gold, 2016
Benjamin Heintz   +2 more
openalex   +1 more source

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