Results 151 to 160 of about 1,882,464 (376)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

geoschem/geos-chem: GEOS-Chem 12.6.2

, 2019
GEOS-Chem 12.6.2 15 Nov 2019 This feature adds more minor fixes for issues discovered after the 12.6.1 release. Now make sure the HEMCO standalone gets the proper met field name and grid resolution Prevent overwriting restart variables H2O2AfterChem and SO2AfterChem if present Fix incorrect vertical flipping of MAPL 3D imports impacting mesospheric ...
openaire   +1 more source

Optimal time-domain combination of the two calibrated output quadratures of GEO 600 [PDF]

, 2005
GEO 600 is an interferometric gravitational wave detector with a 600 m arm-length and which uses a dual-recycled optical configuration to give enhanced sensitivity over certain frequencies in the detection band. Due to the dual-recycling, GEO 600 has two
Ajith, P., Grote, H., Hewitson, M., Hild, S., Lück, H., Smith, J., Strain, K., Willke, B., Woan, G.   +8 more
core   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Preface: special issue on geo-social media analytics [PDF]

, 2018
Feng Chen, Arnold P. Boedihardjo, Chang‐Tien Lu   +2 more
openalex   +1 more source

Atomic Size Misfit for Electrocatalytic Small Molecule Activation

Advanced Functional Materials, EarlyView.
This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong, Changfan Xu, Huaping Zhao, Yong Lei   +3 more
wiley   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Identification of Bacterial Lipopolysaccharide-Associated Genes and Molecular Subtypes in Autism Spectrum Disorder

Pharmacogenomics and Personalized Medicine
Yuanxia He,1,2,* Yun He,2,* Boli Cheng1,2 1Department of Clinical Medicine, North Sichuan Medical College, Nanchong, Sichuan, 637000, People’s Republic of China; 2Department of Pediatrics, Affiliated Hospital, North Sichuan Medical College ...
He Y, He Y, Cheng B
doaj  

Enhancing postmenopausal osteoporosis: a study of KLF2 transcription factor secretion and PI3K-Akt signaling pathway activation by PIK3CA in bone marrow mesenchymal stem cells

Archives of Medical Science
Introduction Mesenchymal stem cells can develop into osteoblasts, making them a promising cell-based osteoporosis treatment. Despite their therapeutic potential, their molecular processes are little known.
Wenjie Ma, Chen Li
doaj   +1 more source

GeAl2‐2xFe2xO3(OH)4 Nanotubes: New Electrocatalyst for Oxygen Evolution Reaction

Advanced Functional Materials, EarlyView.
Fe‐doped imogolite nanotubes are synthesized via a one‐step hydrothermal method with varying Fe substitution ratios x. Structural and spectroscopic analyses confirm homogeneous Fe incorporation while preserving tubular shape. Optimal doping at x = 0.05 enhances optical absorption, narrows band gap, reduces charge transfer resistance, and significantly ...
Yassine Naciri, Jian Li, Wahid Ullah, Fabien Baron, Franck Bourdelle, Stéphan Rouzière, Claire Goldmann, Erik Elkaim, Thomas Bizien, Rachid Belkhou, Delphine Vantelon, Mohamed Nawfal Ghazzal, Erwan Paineau   +12 more
wiley   +1 more source