Results 161 to 170 of about 363,358 (296)
Multi-omics analysis reveals features improving outcomes and immunotherapy resistance in MSS colorectal cancer. [PDF]
Xu H +6 more
europepmc +1 more source
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source
CellMap: precision mapping of cellular landscape in spatial transcriptomics. [PDF]
Liu H +10 more
europepmc +1 more source
Retrieving Geo-Location of Videos with a Divide & Conquer Hierarchical Multimodal Approach
Michele Trevisiol +3 more
openalex +1 more source
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen +12 more
wiley +1 more source
Integrative bioinformatics analysis identifies ubiquitin-related genes and their regulatory networks in hepatoblastoma. [PDF]
Wu J, Xu S.
europepmc +1 more source
Castration‐resistant prostate cancer (CRPC) remains sensitive to ferroptosis, but its intrinsic resistance is poorly understood. Here, we identify NFIB as a master suppressor. SIRT7‐mediated NFIB acetylation drives its liquid–liquid phase separation, which promotes SLC3A2 transcription to inhibit ferroptosis.
Qiunuo Li +11 more
wiley +1 more source
Comprehensive analysis of the potential effect and mechanism of pyroptosis-related genes in treatment-related myeloid tumors. [PDF]
Cheng J, Fang W, Tan H, Zhan X, Zhu X.
europepmc +1 more source

