Results 311 to 320 of about 1,882,464 (376)

CARIBSAT GIS AND GEO-INDICATORS OF NATURALS RISKS IN THE CARIBBEAN BASIN TOOLS FOR COMPARATIVE DIAGNOSTICS AND PREVENTIVE INFORMATION AT REGIONAL SCALE

, 2012
Frédéric Leone, Julien Deymier, Jean-Raphaël Gros-Désormeaux, Marc Morell   +3 more
openalex   +1 more source

Functional analysis of ceRNA network of lncRNA TSIX/miR-34a-5p/RBP2 in acute myocardial infarction based on GEO database

Jiezhong Lin, Jianyi Zhou, Guiting Xie, Xiongwei Xie, Yanfang Luo, Jinguang Liu   +5 more
openalex   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

Machine Learning-Based Transcriptomic Diagnosis of Periodontitis. [PDF]

Int Dent J
Cheng Y, Yang H, Mo H, Xu P.
europepmc   +1 more source

Between History and Pedagogy: Teaching the Philippine National Territorial Imaginary -its 'Geo-Body' -After the 2016 South China Sea Arbitral Award

Romel Regalado Bagares
openalex   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Machine learning-based integration of tumor deposit molecular signatures improves prognostic stratification in colon adenocarcinoma. [PDF]

Int J Colorectal Dis
Wu J, Wu J, Zheng Z, Chen S.
europepmc   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Development of a novel diagnostic model for Alzheimer's disease based on glymphatic system and metabolism-related genes. [PDF]

Front Mol Biosci
Jiang A, Shi D, Que X, Lin Z, Chen Y, Huang Y, Liu C, Wen Y, Zhang S, Huang W.   +9 more
europepmc   +1 more source