Results 31 to 40 of about 363,358 (296)

After the Eruption: A Reply to My Interlocutors

Journal of French and Francophone Philosophy, 2022
Good interlocutors are a blessing, and needless to say, I’m feeling very blessed today. This is especially true for a project in which vision figures so centrally, since we often see most clearly through the parallax of another’s eyes.
Geo Maher
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

LEGOStore: A Linearizable Geo-Distributed Store Combining Replication\n and Erasure Coding [PDF]

, 2021
Hamidreza Zare, Viveck R. Cadambe, Bhuvan Urgaonkar, Chetan Sharma, Praneet Soni, Nader Alfares, Arif Merchant   +6 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Screening and Identification of Potential Hub Genes in Myocardial Infarction Through Bioinformatics Analysis

Clinical Interventions in Aging, 2020
Yong-Wei Yu,1,* Yang-Jing Xue,1,* La-La Qian,2 Zhi Chen,2 Jia-Qun Que,1 Kai-Yu Huang,1 Shuai Liu,1 Ying-Bei Weng,1 Fang-Ning Rong,1 Kang-Ting Ji,1 Jing-Ni Zeng1 1Department of Cardiology, The Second Affiliated and Yuying Children’s Hospital of ...
Yu YW, Xue YJ, Qian LL, Chen Z, Que JQ, Huang KY, Liu S, Weng YB, Rong FN, Ji KT, Zeng JN   +10 more
doaj  

A long-term monitoring of micro-tectonic movements in caves at Cape Kaliakra, Northeast Bulgaria: Correlation with seismic events and precipitation [PDF]

Journal of the Bulgarian Geographical Society
This article aims to present the results of an 11-year monitoring of micro-tectonic movements along dangerous cracks opening in caves at Cape Kaliakra, Northeast Bulgaria.
Nikolai Dobrev, Plamen Ivanov, Konstantin Kostov, Emil Oynakov, Nina Nikolova, Boyko Berov, Orlin Dimitrov, Elena Koleva-Rekalova, Miroslav Krastanov, Rosen Nankin   +9 more
doaj   +3 more sources

Contemporary trends in the development of public procurement law in South Africa

Ruch Prawniczy, Ekonomiczny i Socjologiczny, 2023
This paper explores emerging contemporary trends in the development of South Africa’s public procurement law. Using a doctrinal legal analysis, it identifies two main trends in such development post-democratization, one structural and one substantive ...
Geo Quinot
doaj   +1 more source

Geo-Situation for Modeling Causality of Geo-Events in Knowledge Graphs [PDF]

, 2022
Shirly Stephen, Wenwen Li, Torsten Hahmann   +2 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source