Results 31 to 40 of about 628,123 (310)
International Journal of General Medicine, 2022 Xueru Chen,1,* Kai Gao,2,* Zijin Xiang,1 Yujun Zhang,1 Xiangdong Peng1 1Department of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, People’s Republic of China; 2Department of Gastrointestinal Surgery ...
Chen X, Gao K, Xiang Z, Zhang Y, Peng X
doaj
PON2 blockade overcomes dexamethasone resistance in acute lymphoblastic leukemia
Hematology, 2022 Objectives The high frequency of chemotherapy resistance is ultimately responsible for clinical relapse in acute lymphoblastic leukemia (ALL). Nevertheless, the molecular mechanism relevant to glucocorticoid (GC) resistance remains ambiguous.
Pei-Ye Hui +3 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Geo-Environmental Evaluation of Shewasoor Soil, Kirkuk/ NE Iraq [PDF]
Kirkuk Journal of Science, 2018 The present research aimed to evaluate contamination levels of soil by heavy metals. Eight sites were selected for the collection of soil samples. The soil samples analyzed for eight heavy metals namely As, Pb, Cd, Cr, Co, Cu, Ni, and Zn by using ICP-MS ...
Mustafa J. A. Ali, Omer S. I. Al-Tamimi
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After the Eruption: A Reply to My Interlocutors
Journal of French and Francophone Philosophy, 2022 Good interlocutors are a blessing, and needless to say, I’m feeling very blessed today. This is especially true for a project in which vision figures so centrally, since we often see most clearly through the parallax of another’s eyes.
Geo Maher
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The Twelfth Marcel Grossmann Meeting, 2012 3 pages, contribution to MG12 ...
openaire +3 more sources
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source