Results 181 to 190 of about 265,291 (311)

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source

Assessing geographic variation in women's decision-making power across 720 districts in India, 2016-2021. [PDF]

BMC Womens Health
Eom YJ, Balla S, Rajpal S, Kim R, Subramanian SV.   +4 more
europepmc   +1 more source

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

Advanced Science, EarlyView.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang, Shuhan Duan, Qiuxia Sun, Renkuan Tang, Lintao Luo, Jie Zhong, Zhaxylyk Sabitov, CAGDP Consortium†, Lan‐Hai Wei, Chao Liu, Maxat Zhabagin, Guanglin He   +11 more
wiley   +1 more source

Oilseed rape diseases: geographic variation in stem canker

, 2008
Fitt, B. D. L., Latunde-Dada, A. O., Stonard, J.   +2 more
core  

Geographic Variation in Amputations for Medicare Patients With Diabetic Lower-Extremity Wounds.

JAMA Netw Open
Popescu I, Hernandez H, Plasencia G, Schutz S, Birnbaum D, Gurvey J, Nouvong A, Rowe V, Damberg CL.   +8 more
europepmc   +1 more source

Geographic Variation in Prevalence of Breathlessness: Latitude. [PDF]

Am J Respir Crit Care Med
Currow DC, Kochovska S, Olsson M, Chang S.   +3 more
europepmc   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

Distinct mutational landscape and clonal evolution of POLE-mutated endometrial cancer: geographic variation and insights into multiple classifier status. [PDF]

J Transl Med
Song Y, Gu X, Zhao P, Zhang X, Jia H, Xing X.   +5 more
europepmc   +1 more source

ORBIT‐AMD: Ordinal Risk, Bilateral Imaging, and Trajectory Learning for Age‐Related Macular Degeneration in Multi‐Cohorts

Advanced Science, EarlyView.
Eligibility flow and real‐world AMD burden in the UKB retinal imaging cohort and TMUEH external‐validation cohort. Overview of the ORBIT‐AMD architecture, integrating retinal representation pretraining, bilateral eye‐graph modeling and concept bottleneck learning to support ordered risk, bilateral context, interpretable lesion concepts, longitudinal ...
Xuehao Cui, Dejia Wen, Patrick Yu‐Wai‐Man, Xiaorong Li   +3 more
wiley   +1 more source

Geographic Variation in Morphology and Physiology of <i>Meretrix meretrix</i> (Linnaeus, 1758) Along the Chinese Coast. [PDF]

Animals (Basel)
Bao J, Zhu Y, Liu L, Han S, Wang F, Hu H, Zhang X, Li L, Jiang M.   +8 more
europepmc   +1 more source