A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu +5 more
wiley +1 more source
Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie +17 more
wiley +1 more source
Investigation into the supply-demand relationship of carbon sequestration in the yellow river basin using the optimal parameter geographical detector model. [PDF]
Zhao H +7 more
europepmc +1 more source
UHSR translates complex chemical behavior into clear and explainable equations. Applied to thin‐layer chromatography, it automatically uncovers the mathematical rules linking a molecule's structure to its polarity. This approach matches the accuracy of advanced AI while providing interpretable results, earning greater trust from chemists. The method is
Siyu Lou +4 more
wiley +1 more source
Identifying Drivers Affecting the Spatial Distribution of Suitable Habitat for the Pine Wood Nematode (<i>Bursaphelenchus xylophilus</i>) in China: Insights From Ensemble Model and Geographical Detector. [PDF]
Zhang L +5 more
europepmc +1 more source
A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data
SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang +5 more
wiley +1 more source
Exploring the influencing factors of scrub typhus in Gannan region, China, based on spatial regression modelling and geographical detector. [PDF]
Pan K, Lin F, Xue H, Cai Q, Huang R.
europepmc +1 more source
Real-time traffic monitoring by fusing floating car data with stationary detector data [PDF]
Audenaert, P. +6 more
core +2 more sources
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang +12 more
wiley +1 more source
Spatial stratified heterogeneity analysis of field scale permafrost in Northeast China based on optimal parameters-based geographical detector. [PDF]
Guo Y, Liu S, Qiu L, Zhang C, Shan W.
europepmc +1 more source

