Results 51 to 60 of about 2,353,595 (359)
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Astérion, 2012 In the 16th century, the Holy Roman Empire had a complex political structure. The main features of this structure were the several levels of the political representation and the multiplicity of States under the imperial authority.
Axelle Chassagnette
doaj +1 more source
Conceptions of geographic information systems (GIS) held by senior geography students in Queensland [PDF]
, 2008 Geographical Information Systems (GIS) represent one of the major contributions to spatial analysis and planning of the new technologies. While teachers and others have viewed its potential contribution to geographical education as considerable, it has ...
West, Bryan A.
core +1 more source
Exploring different 'perspectives' in secondary geography: Professional development options [PDF]
, 2002 Significant changes have occurred in the worlds of geography since 1973, and a substantial literature has emerged about these changes and their effects on the 'divide' between secondary and tertiary geographers.
Chalmers, Lex +2 more
core +2 more sources
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
Climate and cultural evolution drove Holocene cropland change in the Huai River Valley, China
iScienceSummary: As an important way of maximizing land productivity by growing more than one crop type in the same field, mixed cropping has been an effective option for sustaining population growth under different climatic conditions since prehistoric period ...
Yanyan Yu +10 more
doaj +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
The Teaching of Geography The Austral Geographies [PDF]
Nature, 1903 PROF. J. W. GREGORY is taking an active part in the promotion of sound geographical instructtion in the land of his adoption. In a lecture recently published he sets forth the. scope of geography and the way in which it should be applied to education. In a series of school-books he shows practically how he would do this for Australian children.
openaire +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source