Results 131 to 140 of about 8,326,295 (377)

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, EarlyView.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source

Predicting the Brexit vote: getting the geography right (more or less) [PDF]

, 2016
In April 2016 in two contributions to this blog Ron Johnston, Kelvyn Jones and David Manley predicted the likely geography of support for Brexit in the EU referendum. In this concluding piece they compare their predictions to the result.
Johnston, Ron, Jones, Kelvyn, Manley, David   +2 more
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Rehabilitated Tailing Piles in the Metropolitan Ruhr Area (Germany) Identified as Green Cooling Islands and Explained by K-Mean Cluster and Random Forest Regression Analyses

Remote Sensing
Urban green spaces, such as parks, cemeteries, and allotment gardens provide important cooling functions for mitigating the urban heat island (UHI) effect. In the densely populated Ruhr Area (Germany), rehabilitated tailing piles (TPs), as relicts of the
Britta Stumpe, Bernd Marschner
doaj   +1 more source

AlphaFold‐Guided Bespoke Gene Editing Enhances Field‐Grown Soybean Oil Contents

Advanced Science, EarlyView.
An AlphaFold‐guided method is developed to functionally optimize soybean sugar transporters and achieve bespoke gene editing of GmSWEET10a/b to improve oil content in an elite soybean cultivar in multi‐year, multi‐site field trials. The combination of AI‐guided protein design and gene editing may unlock a huge potential to improve the genetic trait de ...
Jie Wang, Li Zhang, Shoudong Wang, Xin Wang, Suning Li, Pingping Gong, Mengyan Bai, Arnav Paul, Nathan Tvedt, Hengrui Ren, Maoxiang Yang, Zhihui Zhang, Shaodong Zhou, Jiayi Sun, Xianjin Wu, Huaqin Kuang, Zhenghua Du, Yonghui Dong, Xiaolei Shi, Meina Li, Diwakar Shukla, Long Yan, Yuefeng Guan   +22 more
wiley   +1 more source

Agreements/subagreements Applicable to Wallops, 12 Nov. 1991 [PDF]

The status of space science agreements are noted. A general overview of the Wallops Flight Facility (WFF) is given. The geography, history, and mission of the facility are briefly surveyed. Brief accounts are given of NASA earth science activities at the

core   +1 more source

Mathematics and Morphogenesis of the City: A Geometrical Approach

, 2010
Cities are living organisms. They are out of equilibrium, open systems that never stop developing and sometimes die. The local geography can be compared to a shell constraining its development.
Catherine Gloaguen, G. Chen, J. L. Gross, P. Blanchard, P. Frankhauser, Stephane Douady, Thomas Courtat, Y. I. H. Parish   +7 more
core   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

Modelling Inter-Regional Trade Flows: Data and Methodological Issues in Rhomolo [PDF]

The present paper studies the modelling of inter-regional trade flows in the newly developed general equilibrium model of European Commission, Rhomolo.
d'Artis Kancs, Dirk Stelder, Olga Ivanova   +2 more
core  

Commentary: general principles and analytical frameworks in geography and GIScience

Annals of GIS, 2022
Michael F. Goodchild
doaj   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source