Results 161 to 170 of about 1,108,450 (348)

Comprehensive Insights into Tracheoesophageal Fistula Pathophysiology, Diagnosis, Treatment, and Future Directions

open access: yesAdvanced Science, EarlyView.
Tracheoesophageal fistula (TEF), a pathological trachea‐esophagus connection, arises congenitally or from malignancy/radiotherapy/trauma, causing aspiration and malnutrition. Diagnosis utilizes imaging and endoscopy. Treatment ranges from endoscopic stenting to surgical repair and conservative management.
Gang Li   +10 more
wiley   +1 more source

USP45 Represses Melanoma Development by Deubiquitinating and Stabilizing Tumor Suppressor MRGPRF

open access: yesAdvanced Science, EarlyView.
USP45 acts as a melanoma suppressor by stabilizing MRGPRF, which weakens the PI3K/AKT pathway, suppresses tumor growth, and reduces melanoma cell migration and invasion. Abstract Melanoma, a highly malignant skin cancer, has seen a rising incidence and death toll. MRGPRF is a novel melanoma suppressor that inhibits the PI3K/AKT pathway.
Wancong Zhang   +10 more
wiley   +1 more source

Drug Delivery Technologies for the Treatment of Age‐Related Macular Degeneration

open access: yesAdvanced Science, EarlyView.
There are multiple therapeutic agents available for the treatment of both dry age‐related macular degeneration (AMD) and wet AMD. It is essential to continue innovation by introducing new drug delivery technologies that can incorporate those along with patient compliance and the accessibility of the technology into the early stages of research and ...
J Jesus Rodriguez‐Cruz   +4 more
wiley   +1 more source

Different tiers of government in port governance: some general remarks on the institutional geography of ports in Europe and Canada [PDF]

open access: yes
For the last thirty years, port governance has been marked by a new level of complexity which has resulted in the reshaping of the system of actors involved in the organization of ports.
Jean Debrie
core  

Towards a general theory of geographic representation in GIS [PDF]

open access: bronze, 2006
Michael F. Goodchild   +2 more
openalex   +1 more source

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
The neutrophil extracellular traps (NETs) play an important role in reperfusion injury in ischemic stroke. Here, considering the unique vascular localization of NETs, a DNase I‐mediated NETs‐targeting nanoparticle is developed to integrate the catalytic and chemotactic functions of DNase I and achieve the synergistic regulation of the internal and ...
Tongyu Zhang   +7 more
wiley   +1 more source

Transformation of a Silicate Material for Carbon Negative Magnesia‐Based Cement via Electrochemistry

open access: yesAdvanced Science, EarlyView.
The transformation of a magnesium trisilicate material via water electrolysis into precursor phases necessary for magnesium‐based M‐S‐H cement is explored. The dissolution of the material mediated electrochemically is monitored, and the analysis of the resulting phases indicate their suitability as effective precursors for M‐S‐H cement.
Anthony R. Ramuglia   +11 more
wiley   +1 more source

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