Tracheoesophageal fistula (TEF), a pathological trachea‐esophagus connection, arises congenitally or from malignancy/radiotherapy/trauma, causing aspiration and malnutrition. Diagnosis utilizes imaging and endoscopy. Treatment ranges from endoscopic stenting to surgical repair and conservative management.
Gang Li+10 more
wiley +1 more source
USP45 Represses Melanoma Development by Deubiquitinating and Stabilizing Tumor Suppressor MRGPRF
USP45 acts as a melanoma suppressor by stabilizing MRGPRF, which weakens the PI3K/AKT pathway, suppresses tumor growth, and reduces melanoma cell migration and invasion. Abstract Melanoma, a highly malignant skin cancer, has seen a rising incidence and death toll. MRGPRF is a novel melanoma suppressor that inhibits the PI3K/AKT pathway.
Wancong Zhang+10 more
wiley +1 more source
Geography and the Number of Moduli of Surfaces of General Type [PDF]
Igor Reider
openalex +1 more source
Drug Delivery Technologies for the Treatment of Age‐Related Macular Degeneration
There are multiple therapeutic agents available for the treatment of both dry age‐related macular degeneration (AMD) and wet AMD. It is essential to continue innovation by introducing new drug delivery technologies that can incorporate those along with patient compliance and the accessibility of the technology into the early stages of research and ...
J Jesus Rodriguez‐Cruz+4 more
wiley +1 more source
Different tiers of government in port governance: some general remarks on the institutional geography of ports in Europe and Canada [PDF]
For the last thirty years, port governance has been marked by a new level of complexity which has resulted in the reshaping of the system of actors involved in the organization of ports.
Jean Debrie
core
Towards a general theory of geographic representation in GIS [PDF]
Michael F. Goodchild+2 more
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Trends, geographical variation and factors associated with melatonin prescribing in general practices in England: A practice‐level analysis [PDF]
Mandy Wan, Rukeya Begum, Asia N Rashed
openalex +1 more source
The neutrophil extracellular traps (NETs) play an important role in reperfusion injury in ischemic stroke. Here, considering the unique vascular localization of NETs, a DNase I‐mediated NETs‐targeting nanoparticle is developed to integrate the catalytic and chemotactic functions of DNase I and achieve the synergistic regulation of the internal and ...
Tongyu Zhang+7 more
wiley +1 more source
Tsunami Impact Assessment and Vulnerability Index Development using Computable General Equilibrium (CGE) Model and Geographic Information System (GIS) – A Study on Mie Prefecture, Japan [PDF]
Hajime Tanaka+2 more
openalex +1 more source
Transformation of a Silicate Material for Carbon Negative Magnesia‐Based Cement via Electrochemistry
The transformation of a magnesium trisilicate material via water electrolysis into precursor phases necessary for magnesium‐based M‐S‐H cement is explored. The dissolution of the material mediated electrochemically is monitored, and the analysis of the resulting phases indicate their suitability as effective precursors for M‐S‐H cement.
Anthony R. Ramuglia+11 more
wiley +1 more source