Results 31 to 40 of about 218,297 (244)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Dupin Cyclides as a Subspace of Darboux Cyclides

Mathematics
Dupin cyclides are interesting algebraic surfaces used in geometric design and architecture to join canal surfaces smoothly and to construct model surfaces.
Jean Michel Menjanahary, Raimundas Vidunas   +1 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Developments, Novel Concepts, and Challenges of Current Collectors: From Conventional Lithium Batteries to All‐Solid‐State Batteries

ChemElectroChem
With the innovation and evolution of lithium batteries, different active materials are loaded onto the current collectors, leading to remarkable changes in the components that directly interact with the current collectors.
Ying Zhang, Shenghao Jing, Huaqing Shen, Sijia Li, Yuting Huang, Yuxing Shen, Siliang Liu, Zongliang Zhang, Fangyang Liu   +8 more
doaj   +1 more source

An Impact Assessment of Speed Humps’ Geometric Characteristics and Spacing on Vehicle Speed: An Overview

Infrastructures
This review examines the effect of geometric properties and the spacing of road humps on vehicle speed and noise, with a particular emphasis on South Asian contexts, especially Malaysia.
Nawaf M. Alshabibi
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Geometric Design Methodology for Deployable Self-Locking Semicylindrical Structures

Buildings
Due to their unique bistable characteristics, deployable self-locking structures are suitable for many engineering fields. Without changing the geometrical composition, such structures can be unfolded and locked solely by the elastic deformation of ...
Zhanwei Zhao, Lei Yu
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

The Application Model of the Isolated Door in Interconnected Hazards Warehouse

IEEE Access, 2019
The aim of this paper is to propose new approaches using isolated doors to improve the efficiency of the operating system in a dangerous goods warehouse. Whether the design of isolation door is reasonable or not can be evaluated by four indicators, i.e.,
Fangwei Zhang, Jing Sun, Guan Ke Liew, Wenjing Wang, Jun Ye   +4 more
doaj   +1 more source