Results 41 to 50 of about 234,013 (256)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Unavoidability and Functionality of Nervous System and Behavioral Randomness

Applied Sciences
The basic functioning of the central nervous system is based on the opening and closing of ionic channels in the membranes of neurons. The behavior of ionic channels is considered to be a random process with an exponential probability distribution ...
Carlos M. Gómez, Elena I. Rodríguez-Martínez, María A. Altahona-Medina   +2 more
doaj   +1 more source

Some geometric aggregation operators based on log-normally distributed random variables [PDF]

International Journal of Computational Intelligence Systems, 2014
The weighted geometric averaging (WGA) operator and the ordered weighted geometric (OWG) operator are two of most basic operators for aggregating information.
Xin-Fan Wang, Jian-Qiang Wang, Sheng-Yue Deng   +2 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

An empirical data analysis of "price runs" in daily financial indices: Dynamically assessing market geometric distributional behavior.

PLoS ONE, 2022
In financial time series there are time periods in which market indices values or assets prices increase or decrease monotonically. We call those events "price runs", "elementary uninterrupted trends" or just "uninterrupted trends".
Héctor Raúl Olivares-Sánchez, Carlos Manuel Rodríguez-Martínez, Héctor Francisco Coronel-Brizio, Enrico Scalas, Thomas Henry Seligman, Alejandro Raúl Hernández-Montoya   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

STUDY ON MODELING AND VISUALIZING THE POSITIONAL UNCERTAINTY OF REMOTE SENSING IMAGE [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016
It is inevitable to bring about uncertainty during the process of data acquisition. The traditional method to evaluate the geometric positioning accuracy is usually by the statistical method and represented by the root mean square errors (RMSEs) of ...
W. Jiao, T. Long, S. Ling, G. He
doaj   +1 more source

Geometric Losses for Distributional Learning

CoRR, 2019
Building upon recent advances in entropy-regularized optimal transport, and upon Fenchel duality between measures and continuous functions , we propose a generalization of the logistic loss that incorporates a metric or cost between classes. Unlike previous attempts to use optimal transport distances for learning, our loss results in unconstrained ...
Arthur Mensch, Mathieu Blondel, Gabriel Peyré   +2 more
openaire   +3 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Non-Uniformly Multidimensional Moran Random Walk with Resets

Axioms
In this paper, we investigate the non-uniform m-dimensional Moran walk (Zn(1),…,Zn(m)), where each component process (Zn(j))1≤j≤m, either increases by one unit or resets to zero at each step.
Mohamed Abdelkader
doaj   +1 more source