Results 91 to 100 of about 366,497 (275)

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner   +14 more
wiley   +1 more source

ABOUT EFFICIENT MODELLING OF THE GEOMETRY FOR FINITE ELEMENT ANALYSIS

open access: yesJournal of Industrial Design and Engineering Graphics, 2015
The current CAD platforms provides to user a wide variety of powerful geometric modelling tools, which allows the generation with a high accuracy the 3D geometry of the machinery components. If for achieving the fabrication documentation, the accuracy of
Petru DUMITRACHE
doaj   +4 more sources

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source

Abstract geometry for design in an empirical modelling context [PDF]

open access: yes
We review research from an agenda set out in a previous paper, which investigated the application of definitive programming principles to the implementation of CAD systems. This has led us to the development of a new Empirical Modelling paradigm.
Beynon, Meurig   +3 more
core  

Prediction of the aerodynamic performance of re-usable single stage to orbit vehicles [PDF]

open access: yes, 2011
Re-usable single stage to orbit launch vehicles promise to reduce the cost of access to space, but their success will be particularly reliant on accurate modelling of their aero-thermodynamic characteristics.
Ahmad, Abdul Ossman   +3 more
core  

Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control

open access: yesAdvanced Engineering Materials, EarlyView.
This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian   +4 more
wiley   +1 more source

Phenomenological modeling of geometric metasurfaces

open access: yesOptics Express, 2016
Metasurfaces, with their superior capability in manipulating the optical wavefront at the subwavelength scale and low manufacturing complexity, have shown great potential for planar photonics and novel optical devices. However, vector field simulation of metasurfaces is so far limited to periodic-structured metasurfaces containing a small number of ...
Ye, Weimin   +4 more
openaire   +4 more sources

Fourth-order flows in surface modelling [PDF]

open access: yes, 2013
This short article is a brief account of the usage of fourth-order curvature flow in surface ...
Kang, Ty
core  

Enhancing Corrosion Resistance and Mechanical Strength of 3D‐Printed Iron Polylactic Acid for Marine Applications via Laser Surface Texturing

open access: yesAdvanced Engineering Materials, EarlyView.
Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat   +6 more
wiley   +1 more source

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