Results 51 to 60 of about 4,888,321 (297)
Topological Photonic Media and the Possibility of Toroidal Electromagnetic Wavepackets
Applied Sciences, 2019 This study aims to present a theoretical investigation of a feasible electromagnetic wavepacket with toroidal-type dual vortices. The paper begins with a discussion on geometric phases and angular momenta of electromagnetic vortices in free space and ...
Masaru Onoda
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A super-oscillatory step-zoom metalens for visible light
Beilstein Journal of Nanotechnology, 2022 In recent years, the super-oscillation method based on the fine interference of optical fields has been successfully applied to sub-diffraction focusing and super-resolution imaging.
Yi Zhou +8 more
doaj +1 more source
Sensors, 2023 A novel DAS setup based on geometric phases in coherent heterodyne detection is applied for the first time to the characterisation of the Earth’s subsurface.
Sabahat Shaheen +2 more
doaj +1 more source
phi-g OTDR utilizing geometric phase
, 2023 Geometric phase measured per beat period in a ϕ-OTDR based on coherent heterodyne detection is used to measure strain. Proposed method is robust to polarisation mismatch fading as a polarisation mismatch between interfering beams is not a hindrance to ...
Shaheen, Sabahat +2 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Generalised Geometric Phase [PDF]
, 2023 A generalised notion of geometric phase for pure states is proposed and its physical manifestations are shown. An appreciation of fact that the interference phenomenon also manifests in the average of an observable, allows us to define the argument of ...
Vyas, Vivek M.
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source