Results 51 to 60 of about 154,401 (295)
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Spontaneous Ca2+ Fluctuations Arise in Thin Astrocytic Processes With Real 3D Geometry [PDF]
, 2021 László Héja +3 more
openalex +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Using Particle Filter for Estimating Velocity of Maneuvering Target Being Tracked by Passive Radar
Syrian Journal for Science and InnovationTracking a target is achieved by estimating its range and velocity, and this process has two types: Bistatic Tracking and Cartesian Tracking. In a passive radar system, the bistatic tracking is achieved by processing the bistatic geometry “One non ...
Anas Almanofi , Ali Kazem
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini +13 more
wiley +1 more source
Signature verification by geometry and image processing
Nonlinear EngineeringIn this article, we present an algorithm to determine the authenticity of a signature with high probability. This study addresses the increasing need for robust and accurate methods of verifying offline signatures, which are crucial in various legal and ...
Jaber Ebaa Abdulsattar +2 more
doaj +1 more source
The Geometry of Signal Detection with Applications to Radar Signal Processing
Entropy, 2016 The problem of hypothesis testing in the Neyman–Pearson formulation is considered from a geometric viewpoint. In particular, a concise geometric interpretation of deterministic and random signal detection in the philosophy of information geometry is ...
Yongqiang Cheng +4 more
doaj +1 more source
Point Cloud Attacks in Graph Spectral Domain: When 3D Geometry Meets Graph Signal Processing [PDF]
, 2022 Daizong Liu, Wei Hu, Xin Li
openalex +1 more source
Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu +16 more
wiley +1 more source