Results 51 to 60 of about 2,225,279 (261)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Living at the wadi – integrating geomorphology and archaeology at the oasis of Qurayyah (NW Arabia)

Journal of Maps, 2019
The archaeological site Qurayyah, situated in the NW of the Tabuk Province of Saudi Arabia, has been repeatedly described as one of the largest and most significant oases of Northwestern Arabia.
Laura Hüneburg, Philipp Hoelzmann, Daniel Knitter, Bernd Teichert, Christiane Richter, Christopher Lüthgens, Abdullah S. Alsaud, Marta Luciani   +7 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Geomorphology of marine and transitional terraces and raised shorelines between Punta Paulo and Porvenir, Tierra del Fuego, Straits of Magellan – Chile

Journal of Maps, 2017
This paper presents a coastal geomorphology map of some of the Chilean region of the Straits of Magellan, and is based on a combined geomorphological and sedimentological approach applicable to a larger section of the coast. The mapped area is located in
Sandro DeMuro, Antonio Brambati, Sira Tecchiato, Marco Porta, Angelo Ibba   +4 more
doaj   +1 more source

Reconstruction of Grønfjordbreen dynamics (West Spitsbergen) in the Holocene

Лëд и снег, 2017
In the past 80 years, the Grønfjord Glacier front retreated for a distance longer than 2.5 km, and thus, a big part of the proglacial zone became free of ice.
O. V. Kokin, A. V. Kirillova
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Development of a database structure for the first Geomorphological map of Greece at 1:1,000,000 scale

European Journal of Geography
Geomorphological maps offer researchers multiple advantages when studying an area, as they can provide insights into the formation processes of the observed landforms, as well as their possible evolution in the future.
Alexandra Zervakou, Alexandros Petropoulos, Niki Evelpidou, Eirini Zananiri, Giannis Saitis, Evangelos Spyrou, Dionysios Goutis, Hampik Maroukian   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Geomorphological map of Byers Peninsula, Livingston Island

, 1996
The bedrock geology of the peninsula is described briefly as Upper Jurassic to Lower Cretaceous marine sedimentary, volcanic and volcaniclastic rocks, intruded by igneous bodies.
Thomson, M.R.A., Martinez de Pison, E., Arche, Alfredo, Bjorck, Svante, Hatway, B., Serrano, Enrique, Hjort, Christian, Lomas, Simon, Zale, Rolf, Ellis-Evans, John Cynan, Hernandez-Cifuentes, F., Ingolfsson, Olafur, Lopez-Martinez, Jernimo, King, S., Ising, J.   +14 more
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source