Palladium‐Catalyzed Annulations of an Anti‐Bredt Olefin
We report metal‐catalyzed trappings of a [2.2.1]‐bridged bicyclic anti‐Bredt olefin (ABO). The methodology yields unusual heterocyclic products and is expected to prompt the further development of unconventional reactions, including metal‐catalyzed processes of ABOs and other strained olefins. ABSTRACT A famous class of alkene‐containing compounds that
Zach G. Walters +3 more
wiley +2 more sources
ABSTRACT Arthrogryposis multiplex congenita (AMC) is a group of rare congenital conditions, characterized by multiple joint contractures but may involve any body system including central nervous system. AMC is etiologically heterogeneous, with over 400 genetic and many non‐genetic causes implicated in its prenatal development.
Shahrzad Nematollahi +20 more
wiley +1 more source
Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides
Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok +4 more
wiley +2 more sources
Translation and Cross‐Cultural Adaptation of the Chronic Rhinosinusitis Control Test for Global Use
ABSTRACT Introduction The Chronic Rhinosinusitis Control Test (CRCT) is a patient‐reported outcome measure (PROM) written in English that is psychometrically validated to measure chronic rhinosinusitis control. Because the availability of translated PROMs is a driver of data equity—collection of data that is fair and generally representative—our ...
Hye K. Pae +52 more
wiley +1 more source
North American Delphi Consensus Study on Sinonasal Malignancy Survivorship Care
ABSTRACT Background Survival for patients with sinonasal cancers has improved over the past decades, but there are no dedicated survivorship guidelines for this cohort. Objective To understand experts’ priorities and perspectives on key survivorship tenets (surveillance, second tumor screening, toxicity, and symptom management).
Matheus Sewastjanow‐Silva +18 more
wiley +1 more source
Sociodemographic and maternal predictors of elevated blood lead levels during pregnancy in Adjara, Georgia. [PDF]
Sikharulidze S +6 more
europepmc +1 more source
Objective To evaluate the effectiveness and safety of ocrelizumab in self‐identified black and Hispanic people with relapsing multiple sclerosis. Methods The Characterization of Ocrelizumab in Minorities with Multiple Sclerosis (CHIMES) trial, a prospective, open‐label, single‐arm, phase 4 study, intentionally recruited underrepresented populations in ...
Lilyana Amezcua +16 more
wiley +1 more source
Temporal trends and future projections of fertility and birth rates in Georgia: a retrospective observational study. [PDF]
Khachidze N +5 more
europepmc +1 more source
Limited Sex-Based Differences in Viral Outcomes of ART-Treated SIV/SHIV Infection. [PDF]
Endrias K +12 more
europepmc +1 more source
Work-life realities of doctors in Georgia and their impact on mental health and work-related well-being: A cross-sectional study. [PDF]
Asanidze E +9 more
europepmc +1 more source

