Results 41 to 50 of about 268,438 (250)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

COLOUR REVOLUTIONS AND PARLIAMENTARIANISM IN THE CONTEXT OF DEMOCRATIZATION ON POST-SOVIET SPACE

open access: yesСравнительная политика, 2015
Main approaches to the studies of internal and external causes of colour revolutions in Georgia, Kyrgyzstan and the Ukraine are reviewed. The article considers colour revolutions in the context of the fourth wave of democratization and concludes that ...
A. M. Akmatalieva
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

2020 parliamentary elections in Georgia: Results and geographical peculiarities

open access: yesEuropean Spatial Research and Policy, 2021
The article aims to show the main political-geographic trends of the 2020 parliamentary elections in Georgia. The political systems of the post-Soviet counties are still imperfect and fragile.
Revaz Gachechiladze, Giorgi Gogsadze
doaj   +1 more source

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

open access: yesArthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah   +13 more
wiley   +1 more source

Gürcistan Osetlerinde Kimlik: Lagodekhi ve Kaspi Örneği

open access: yesVakanüvis Uluslararası Tarih Araştırmaları Dergisi, 2017
Bu makalede Gürcistan, özellikle Şida Kartli ve Kakheti vilayetlerindeki Osetlerin kimliğinin günümüzdeki durumu, Gürcü toplumuyla ilişkileri ve Kuzey-Güney Osetya ile ilişkileri üzerine odaklanmıştır.
Keisuke Wakizaka
doaj   +1 more source

The Association of Physical Function With Psychosocial Patient‐Reported Outcomes in People With Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey   +8 more
wiley   +1 more source

THE PROBLEMS OF POLITICAL INTERACTION BETWEEN RUSSIA AND COUNTRIES OF THE SOUTH CAUCASUS AT THE TURN OF XX-XXI CENTURIES

open access: yesСовременная наука и инновации, 2022
The article analyzes the development of Russia's foreign policy in the South Caucasian direction in the second half of the 90s of the XX century - the beginning of the 2000s, Particular attention is paid to the identification of objective and subjective ...
Boris Georgievich Koybaev
doaj  

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

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