Results 141 to 150 of about 102,243 (291)

A Phase 2 Trial of Hydroxychloroquine in Individuals at Risk for Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Individuals with serum elevations of anti–cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such at‐risk individuals.
Kevin D. Deane, Christopher C. Striebich, Marie L. Feser, James R. O'Dell, Judith A. James, Jeffrey A. Sparks, John M. Davis III, Jonathan Graf, Maureen A. McMahon, Elizabeth B. Solow, Lindsy J. Forbess, Athan Tiliakos, Elena Schiopu, Maria I. Danila, Diane L. Horowitz, Jonathan Kay, Colin D. Strickland, Joel M. Guthridge, Cristina Arriens, Jennifer M. Grossman, M. Kristen Demoruelle, Elizabeth A. Bemis, Ashley Frazer‐Abel, Chelsie L. Fleischer, David A. Fox, Ted R. Mikuls, Melissa Greenleaf, Kate York, Sarah Walker, Lynette Keyes‐Elstein, Margie Byron, Janel Fedler, Ellen A. Goldmuntz, V. Michael Holers   +33 more
wiley   +1 more source

Exploratory Analysis of Candidate Gene SNPs in Relation to Cervical Cancer Susceptibility in Georgian Women. [PDF]

Cancer Control
Surmava S, Kvaratskhelia E, Davitashvili B, Vardiashvili N, Kharebashvili N, Zarandia M, Ahmad S, Abzianidze E, Kankava K.   +8 more
europepmc   +1 more source

Traditional and Innovative Processing of Georgian Myrobalan Plum (P. cerasifera Ehrh): Effects on Phytochemical Content. [PDF]

Food Sci Nutr
Putkaradze J, Vanidze M, Ghoghoberidze S, Davitadze R, Kalandia A.   +4 more
europepmc   +1 more source

Defining Optimally Safe and Effective Blood Levels of Hydroxychloroquine in Lupus: An Important Step Toward Precision Drug Monitoring

Arthritis &Rheumatology, EarlyView.
Objective Using a hydroxychloroquine (HCQ) dose of 5 mg/kg/day in systemic lupus erythematosus (SLE) is associated with a higher risk of flares; HCQ blood level monitoring could be a better way to adjust the HCQ dose. We studied the upper threshold for a reference range of HCQ levels to inform routine monitoring.
Shivani Garg, Benoît Blanchet, Yann Nguyen, Fauzia Hollnagel, Ada Clarke, Michelle Petri, Murray B. Urowitz, John G. Hanly, Caroline Gordon, Sang‐Cheol Bae, Juanita Romero‐Diaz, Jorge Sanchez‐Guerrero, Ann E. Clarke, Sasha Bernatsky, Daniel J. Wallace, David A. Isenberg, Anisur Rahman, Joan T. Merrill, Paul R. Fortin, Dafna D. Gladman, Ian N. Bruce, Ellen M. Ginzler, Mary Anne Dooley, Rosalind Ramsey‐Goldman, Susan Manzi, Andreas Jönsen, Graciela S. Alarcón, Ronald F. Van Vollenhoven, Cynthia Aranow, Véronique Le Guern, Meggan Mackay, Guillermo Ruiz‐Irastorza, S. Sam Lim, Murat Inanc, Kenneth C. Kalunian, Søren Jacobsen, Christine A. Peschken, Diane L. Kamen, Anca Askanase, Jill Buyon, Julie Chezel, Alicja Puszkiel, Nathalie Costedoat‐Chalumeau   +42 more
wiley   +1 more source

The lack of legal protections in the United States to prevent commercializing the dead for education and research: Consequences and risks to anatomists

Anatomical Sciences Education, EarlyView.
Abstract A lack of minimum legal standards for body donation programs undermines recent strides by anatomy professionals to promote ethical best practices in the United States (US). In particular, the commercialization of the dead by nontransplant tissue banks poses a risk to the public trust in academic body donation programs.
Laura E. Johnson
wiley   +1 more source

Population-specific calibration and validation of an open-source bone age AI. [PDF]

Sci Rep
Rassmann S, Abashishvili L, Melikidze E, Sukhiashvili A, Lartsuliani M, Chkhaidze I, Tskhvediani N, Gordeziani T, Kvaratskhelia E, Kheladze N, Rekhviashvili M, Rodonaia S, Sukhitashvili N, Urushadze N, Krawitz P, Tkemaladze T, Javanmardi B.   +16 more
europepmc   +1 more source

Integrating agro‐residue valorization and clean hydrogen production: coconut fiber‐based catalysts for NaBH4 hydrolysis

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract A novel phosphoric acid‐treated green coconut fiber (GCF‐C) was developed as a catalyst for hydrogen production from the hydrolysis of sodium borohydride (NaBH4). Characterization techniques confirmed structural modifications, including X‐ray diffraction, scanning electron microscopy, X‐ray fluorescence, Fourier transform infrared, and ...
Isabelly Silveira Freitas, Francisco Izaias da Silva Aires, Dayana Nascimento Dari, Jacob Tchiyeke António Kandjila, Maurício Quintas Salamba, Diego Lomonaco, Monalisa Moura de Oliveira, Pierre Basílio Almeida Fechine, Rafael Leandro Fernandes Melo, Alan Silva de Menezes, Marcos Carlos de Mattos, Leonardo Farias Serafim, Maria Cristiane Martins de Souza, Ada Amelia Sanders Lopes, John Herbert da Silva Felix, Eveline de Abreu Menezes, José Cleiton Sousa dos Santos   +16 more
wiley   +1 more source

Ischemic Stroke in a 28-Year-Old Young Adult Associated With Chronic Triptan and Non-Steroidal Anti-Inflammatory Drug (NSAID) Use. [PDF]

Cureus
Babukhadia N, Jangirashvili T, Shengelia L.   +2 more
europepmc   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Correction: Duration of Hospitalization for Hip Arthroplasty: Influence of Clinical-Biological Factors and Timing of the Intervention. [PDF]

Cureus
Danet A, Spiridonica R, Iacobescu GL, Iordache S, Popa M, Rascu AS, Cirstoiu C.   +6 more
europepmc   +1 more source