Results 121 to 130 of about 2,958 (288)

Differential Water Networks Guide Selectivity Optimization of a Cell Active BPTF Inhibitor in Neuroblastoma

open access: yesAngewandte Chemie, EarlyView.
BZ2 is a second‐generation Bromodomain PHD finger Transcription Factor (BPTF) inhibitor with improved selectivity over Class I and Class IV BRD off‐targets identified in our previously reported inhibitor, BZ1. Structural analyses reveal that water network engagement is key to this selectivity.
Kesavan Babu   +19 more
wiley   +2 more sources

The International Consortium for Arthrogryposis: A Collaborative Framework for Early Detection, Care, Research, and Education

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis multiplex congenita (AMC) is a group of rare congenital conditions, characterized by multiple joint contractures but may involve any body system including central nervous system. AMC is etiologically heterogeneous, with over 400 genetic and many non‐genetic causes implicated in its prenatal development.
Shahrzad Nematollahi   +20 more
wiley   +1 more source

North American Delphi Consensus Study on Sinonasal Malignancy Survivorship Care

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Survival for patients with sinonasal cancers has improved over the past decades, but there are no dedicated survivorship guidelines for this cohort. Objective To understand experts’ priorities and perspectives on key survivorship tenets (surveillance, second tumor screening, toxicity, and symptom management).
Matheus Sewastjanow‐Silva   +18 more
wiley   +1 more source

The Georgian Orthodox Church in current Georgian policy

open access: yesCentral Asia and the Caucasus, 2009
For historical reasons the Georgian Orthodox Church (GOC) has always been a subject of Georgian policy despite its separation from the state registered in the country's Constitution. At all times religion not only confirmed and preserved the nation's spiritual values-it served the national and state interests. Today, rapidly unfolding globalization has
openaire   +1 more source

Efficacy and Predictors of Response to Biologic Therapy and Endoscopic Sinus Surgery in Patients With Nasal Polyps: A Systematic Review

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Biologics and endoscopic sinus surgery (ESS) treat refractory chronic rhinosinusitis with nasal polyposis (CRSwNP), but direct comparisons are lacking. We synthesized efficacy and subgroup data across randomized controlled trials (RCTs) of biologics and ESS.
Arun Chakravorty   +13 more
wiley   +1 more source

Factors associated with stroke after COVID-19 vaccination: a statewide analysis. [PDF]

open access: yesFront Neurol, 2023
Nahab F   +6 more
europepmc   +1 more source

Cortical Thickness and White Matter Surface Morphology in Tourette Syndrome: A Cohort Study

open access: yesAnnals of Neurology, EarlyView.
Objective To examine cortical thickness and white matter surface morphology in a large sample of individuals with Tourette syndrome (TS) and neurotypical controls across the lifespan, and to assess associations with symptom severity, comorbidities, and medication use.
Sahar Delavari   +8 more
wiley   +1 more source

Strategies for Controlling Blood Pressure Among Low-Income Populations in Georgia

open access: yesPreventing Chronic Disease, 2008
BackgroundIn Georgia an estimated 32% of blacks and 28% of whites have high blood pressure. In 2004 the rate of death from stroke in Georgia was 12% higher than the national average, and blacks in the state have a 1.4 times greater rate of death from ...
Roberta Constantine, PhD   +6 more
doaj  

Layperson knowledge of heart attacks in the state of Georgia, USA. [PDF]

open access: yesHealth Psychol Res, 2023
Sajja S, Stead T, Mangal R, Ganti L.
europepmc   +1 more source

THE LAST ROYAL DYNASTY OF IRAN AND GEORGIANS

open access: yes, 2015
https://geohistory.humanities.tsu.ge/ge/procedings/83-shromebi/163-shromebi-9.htmlRepresentatives of Georgian royal and princely houses had closer ties with the ruling dynasties of Iran. In the presented article we tried to find out as more as possible
ჯავახიშვილი, ნიკო
core  

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