Results 141 to 150 of about 5,134,159 (382)
Geriatric assessment is superior to oncologists’ clinical judgement in identifying frailty
British Journal of Cancer, 2017 Background:Frailty is a syndrome associated with increased vulnerability and an important predictor of outcomes in older cancer patients. Systematic assessments to identify frailty are seldom applied, and oncologists’ ability to identify frailty is ...
Lene Kirkhus +8 more
semanticscholar +1 more source
Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription
Advanced Science, EarlyView.This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen +14 more
wiley +1 more source
Factors Associated with Sustainability of Integrated Geriatric Health Post in Tabanan, Bali [PDF]
, 2018 Background: Much has been written recently about the need to develop more integrated care for older people. The term comprehensive geriatric assessment, is a form of integrated care for older people that is used to describe the practice of specialist ...
Peratiwi, I. (Indra ) +1 more
core
A systematic review of the relationship between behavioral and psychological symptoms (BPSD) and caregiver well-being [PDF]
, 2016 Background: Behavioural and psychological symptoms in dementia (BPSD) are important predictors of institutionalisation as well as caregiver burden and depression. Previous reviews have tended to group BPSD as one category with little focus on the role of
Charlesworth, Georgina +4 more
core +4 more sources
Geriatric Assessment: Precision Medicine for Older Adults With Cancer [PDF]
, 2018 Grant R. Williams
openalex +1 more source
Advanced Science, EarlyView.This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang +12 more
wiley +1 more source
Incidence and risk factors of Vancomycin-induced thrombocytopenia: a six-year real-world study
BMC Infectious DiseasesObjectives Drug-induced thrombocytopenia has been reported for numerous drugs. Vancomycin-induced thrombocytopenia (VIT) is infrequently and often under-recognized. VIT can lead to the serious consequences of some life-threatening bleeding, especially in
Yuanchao Zhu +4 more
doaj +1 more source
COMPrehensive geriatric AsseSSment and multidisciplinary team intervention for hospitalised older adults (COMPASS): a protocol of pragmatic trials within a cohort [PDF]
, 2022 Jung‐Yeon Choi +15 more
openalex +1 more source
Advanced Science, EarlyView.Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao +36 more
wiley +1 more source
Aging Clinical and Experimental Research, 2018 BackgroundMultimorbidity and frailty are often associated and Comprehensive Geriatric Assessment (CGA) is considered the gold standard of care for these patients.AimsThis study aimed to evaluate the effect of outpatient Comprehensive Geriatric Assessment
A. Mazya, P. Garvin, A. Ekdahl
semanticscholar +1 more source