Results 61 to 70 of about 139,486 (303)

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Geriatric assessment to predict survival in older allogeneic hematopoietic cell transplantation recipients

Haematologica, 2014
Allogeneic hematopoietic cell transplantation is increasingly utilized in older adults. This study prospectively evaluated the prognostic utility of geriatric assessment domains prior to allogeneic transplantation in recipients aged 50 years and over ...
Lori S. Muffly, Masha Kocherginsky, Wendy Stock, Quynh Chu, Michael R. Bishop, Lucy A. Godley, Justin Kline, Hongtao Liu, Olatoyosi M. Odenike, Richard A. Larson, Koen van Besien, Andrew S. Artz   +11 more
doaj   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Comprehensive geriatric assessment: recognition of identified geriatric conditions by community-dwelling older persons

, 2016
Objectives: to study (i) the prevalence of geriatric conditions in community-dwelling older persons at increased risk of functional decline and (ii) the extent to which older persons recognise comprehensive geriatric assessment (CGA)-identified ...
Bol, Wietske, Hoff, Eva, Suijker, Jacqueline J., Buurman, Bianca M., de Rooij, Sophia E., ter Riet, Gerben, van Charante, Eric P. Moll, van Rijn, Marjon, Moll van Charante, Eric P.   +8 more
core   +1 more source

Implementation and evaluation of a geriatric-oncology model of care for older adults with lung cancer

, 2023
Care of the older cancer population is complex and challenging. Older adults are underrepresented in clinical trials, which drive oncology treatment.
Bray, Victoria J. (R21151), Campisi, Josephine, Cara Gollon, Katherine Bell, Abhijit Pal, Elise Tcharkhedian, Shalini Vinod, Bell, Katherine, Josephine Campisi, Sau Kwan Seto, Megan Berry, Victoria Bray, Ahmed, Elhassan, Khoo, Angela, Seto, Sau K., Elhassan Ahmed, Berry, Megan, Pal, Abhijit, Angela Khoo, Tcharkhedian, Elise, Thomas Tran, Gollon, Cara, Vinod, Shalini K., Tran, Thomas   +23 more
core   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Risk factors of linezolid-associated hyponatremia from a retrospective case–control study: decreased serum albumin as a selective predictor in elder patients

Annals of Medicine
Background The incidence of linezolid-associated hyponatremia is approximately 20% in real-world studies. However, there are limited case reports and rare research on linezolid-induced hyponatremia.
Liang Liang, Bo-Lin Zhu, Di Chen, Ming Zhao, Yuan-Chao Zhu, Fei Zhao, Peng-Fei Jin, Yang Ju   +7 more
doaj   +1 more source

Preparing medical graduates to care for geriatric patients: A case study of the undergraduate medical curriculum at a South African university

South African Family Practice, 2020
Background: Medical schools in South Africa must be responsive to the health needs of the rapidly ageing population. Reports of the poor quality of care received by elderly patients raises concerns about the training of medical students.
Keshena Naidoo, Jacqueline van Wyk
doaj   +1 more source

Persistent Bilateral [18F]THK5351 and Migrating Unilateral [18F]FDG Uptake in Anti‐LGI1 Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Anti–leucine‐rich glioma‐inactivated 1 encephalitis (LGI1‐E) can cause persistent cognitive deficits, but the mechanisms remain unclear. A 40‐year‐old woman with LGI1‐E presented with subacute cognitive deficits and showed mild left medial temporal lobe (MTL) swelling and fluid‐attenuated inversion recovery (FLAIR) hyperintensity on initial ...
Yusuke Akitomi, Kenichiro Taira, Masanori Kurihara, Kenji Ishibashi, Kenji Ishii, Fumio Suzuki, Aya Midori Tokumaru, Makoto Hara, Atsushi Iwata   +8 more
wiley   +1 more source

A multidimensional approach to older patients during COVID-19 pandemic: a position paper of the Special Interest Group on Comprehensive Geriatric Assessment of the European Geriatric Medicine Society (EuGMS).

, 2023
20.500.12530/87908The COVID-19 pandemic has been a dramatic trigger that has challenged the intrinsic capacity of older adults and of society. Due to the consequences for the older population worldwide, the Special Interest Group on Comprehensive ...
Members of the Special Interest Group on Comprehensive Geriatric Assessment of the EuGMS (European Geriatric Medicine Society), Pilotto, Alberto, Palmer, Katie, Custodero, Carlo, Sanchez-Garcia, Elisabet Maria, Topinkova, Eva, Polidori, Maria Cristina   +6 more
core   +1 more source