Results 241 to 250 of about 146,183 (351)

Even at 100+: Acute Exercise Modulates Inflammatory Pathways in Centenarians

open access: yesAging Cell, EarlyView.
Targeted‐proteome analysis suggests that a single acute exercise session may attenuate inflammation at the end of the human lifespan. ABSTRACT Centenarians exhibit remarkable disease resilience despite chronic low‐grade inflammation. We investigated the inflammation‐related proteome response to acute exercise in seven centenarians (100–104 years ...
Abel Plaza‐Florido   +12 more
wiley   +1 more source

Cognitive and behavioural predictors of survival in Alzheimer disease:results from a sample of treated patients in a tertiary-referral memory clinic [PDF]

open access: yes, 2012
Agüero-Torres   +59 more
core   +1 more source

Identification of Functional Cellular Markers Related to Human Health, Frailty and Chronological Age

open access: yesAging Cell, EarlyView.
Human skin fibroblasts in vitro preserve the memory of age and health. ABSTRACT Aging leads to a decline in physiological reserves, an increase in age‐related diseases, reduced functional ability and a shortened healthspan. While molecular markers of chronological aging exist, their link to general health and intrinsic capacity (IC), a composite ...
Chloé Brodeau   +21 more
wiley   +1 more source

A Metabolite Score of Unintentional Weight Loss Explained a Substantial Proportion of Associated Mortality and Mobility Limitation Risk in a Biracial Older Cohort

open access: yesAging Cell, EarlyView.
A metabolite‐based score for short‐term unintentional weight loss was independently associated with mortality and mobility limitation risks in healthy older adults. It accounted for over 20% of the excess risk linked to unintentional weight loss, independent of lifestyle and medical history, suggesting a shared metabolic mechanism that remains ...
Shanshan Yao   +7 more
wiley   +1 more source

A cross-sectional analysis of fall risk among institutionalized older adults in Malaysia. [PDF]

open access: yesBelitung Nurs J
Zohari Z   +7 more
europepmc   +1 more source

Associations of Skin Biomechanical Properties With Biological Aging Clocks and Longitudinal Changes in Intrinsic Capacity in Adults Aged 20–93: The INSPIRE‐T Project

open access: yesAging Cell, EarlyView.
This study assessed skin biomechanics using the Cutometer in 441 community‐dwelling adults aged 20–93 from the INSPIRE‐T cohort. We demonstrated that skin elasticity and viscoelasticity parameters were associated with the intrinsic capacity (IC) score, a functional marker of healthy aging encompassing cognition, locomotion, psychology, vitality, and ...
Wan‐Hsuan Lu   +85 more
wiley   +1 more source

Strategic intelligence monitor on personal health systems phase 3 (SIMPHS3). Integrated care programme for older in- and out-patients University Hospital of Getafe (Spain)., case study report [PDF]

open access: yes, 2015
Abadie, Fabienne   +6 more
core   +1 more source

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