Results 61 to 70 of about 149,337 (331)

Gait speed characteristics and Its spatiotemporal determinants in nursing home residents: A cross-sectional study [PDF]

open access: yes, 2019
Fien, S ORCiD: 0000-0003-0181-5458BACKGROUND AND PURPOSE: Low and slowing gait speeds among nursing home residents are linked to a higher risk of disability, cognitive impairment, falls, and mortality.
Climstein, Mike   +4 more
core   +2 more sources

Genetically determined body mass index is associated with diffuse large B‐cell lymphoma in polygenic and Mendelian randomization analyses

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Obesity has been linked to the risk of non‐Hodgkin lymphoma (NHL), but the evidence remains inconclusive. Here, the authors investigate the possibility of shared genetic risk factors between obesity and four common NHL types. Drawing on data from 8 genome‐wide association studies, they found that a higher genetically determined BMI was ...
Amy Moore   +74 more
wiley   +1 more source

A critical literature review exploring the challenges of delivering effective palliative care to older people with dementia in the acute hospital setting [PDF]

open access: yes, 2008
Aim. This paper considers the challenges of delivering effective palliative care to older people with dementia and the possible strategies to overcome barriers to endof-life care in these patients. Background.
Birch, Deborah, Draper, Janet
core   +1 more source

The Fibrosis‐4 score is associated with overall mortality and severe haematological toxicity in older patients with cancer: Analysis of two prospective cohort studies

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Liver function decreases with age, affecting the metabolism of many chemotherapy drugs. For older cancer patients, however, a standardized liver status screening method is lacking. Here, Fibrosis‐4 (FIB‐4) score was investigated for its utility as a non‐invasive method in predicting treatment toxicity and mortality in cancer patients age 70
Victoire de Salins   +14 more
wiley   +1 more source

An investigation of factors associated with depression in older adults

open access: yes, 1989
As the population ages, there is a need for continued research into the etiology of geriatric depression and improved ways to detect individuals at risk for developing this disorder.
Mayhew, Katherine Mary
core   +1 more source

Geriatric pharmacotherapy : optimisation through integrated approach in the hospital setting [PDF]

open access: yes, 2016
Since older patients are more vulnerable to adverse drug-related events, there is a need to ensure appropriate prescribing in these patients in order to prevent misuse, overuse and underuse of drugs.
A Corsonello   +63 more
core   +1 more source

Anti‐Her2 therapy patterns in metastatic breast cancer—Real‐world data suggest undertreatment

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Although human epidermal growth factor 2‐positive (HER2+) breast cancer is an aggressive malignancy, significant survival benefits are possible with targeted anti‐HER2 therapies. Whether these therapies are used as recommended, however, is unknown. Here, the authors investigated data from population‐based registries in Norway to assess anti‐
Kathrine F. Vandraas   +9 more
wiley   +1 more source

Impact of geriatric impairments on outcomes of single‐agent immunotherapy in solid tumors

open access: yesInternational Journal of Cancer, EarlyView.
What's New? This study comprehensively assesses the impact of frailty and geriatric impairments on key clinical outcomes of single‐agent immunotherapy in older adults with solid tumors. Using prospective multicenter data, the authors demonstrate that frailty is significantly associated with higher rates of all‐cause hospitalization and mortality ...
Asli Özkan   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy