Results 181 to 190 of about 211,526 (242)

Transfer learning identifies bacterial signatures for cross‐regional diagnosis of type 2 diabetes and enable stage‐sensitive dietary fiber intervention

open access: yesiMetaOmics, EarlyView.
DeepMicroFinder is a deep learning framework designed to update the existing disease diagnosis model to generate a transfer model by leveraging region‐specific microbiome datasets and transfer learning approach. This framework effectively overcomes the limitation of regional effects in the gut microbiome, enabling accurate cross‐regional disease ...
Qunye Zhang   +26 more
wiley   +1 more source

Efficacy and biomarker analysis of neoadjuvant disitamab vedotin (RC48‐ADC) combined immunotherapy in patients with muscle‐invasive bladder cancer: A multi‐center real‐world study

open access: yesiMeta, EarlyView.
In this study, 102 cisplatin‐ineligible patients with muscle‐invasive bladder cancer (MIBC) who received neoadjuvant RC48‐ADC combined with immunotherapy were included. We evaluated the pathological responses and explored multiple clinical characteristics to identify independent predictive indicators of the efficacy. The results showed that neoadjuvant
Jiao Hu   +33 more
wiley   +1 more source

The influence of microbiome‐derived amino acids metabolites in shaping the glioma immunosuppressive microenvironment

open access: yesInterdisciplinary Medicine, EarlyView.
Left: The disruption of the balance between carcinogenic bacteria and probiotics mediated by antibiotics, protein, and glucose intake. Middle: The gut microbiota‐derived amino acids, primarily through tryptophan, tyrosine, arginine, and branched‐chain amino acid pathways, regulate glioma development via mechanisms such as AHR activation, metabolic ...
Qianquan Ma   +10 more
wiley   +1 more source

Reimagining pharmacy processes for expanding hospital at‐home care in Singapore: A qualitative study

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, EarlyView.
Abstract Introduction Mobile Inpatient Care at Home (MIC@Home) is an alternative acute care model that offers care within patients' homes instead of in traditional hospital settings. This qualitative study seeks to investigate existing perspectives on MIC@Home and the challenges associated specifically with its provision of pharmacy services, and ...
Brian Lee   +3 more
wiley   +1 more source

Effectiveness of XR‐Based Exposure Therapy for Phobic Disorders

open access: yesJournal of Counseling &Development, EarlyView.
ABSTRACT Research on anxiety and posttraumatic stress disorder (PTSD) indicates that virtual reality and related technologies are effective tools for therapy. Given the similar underlying mechanism of these disorders to phobias, it is thought by researchers in mental health care that VR‐based exposure therapies would have similar treatment outcomes ...
Richard Lamb   +5 more
wiley   +1 more source

Reference Intervals of Hematological Parameters Among Healthy Adults in Northern Sudan: A Community‐Based Cross‐Sectional Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Two hundred fifty‐three adults were enrolled in a cross‐sectional study conducted in Northern Sudan. The RVs of hemoglobin 9.71–16.10 g/dL, red blood cells (RBC) 3.66–5.79 × 106/mm3, hematocrit (HCT) 28.02%–46.75%, mean corpuscular volume (MCV) 64.02–95.65 fL, mean corpuscular hemoglobin (MCH) 21.57–33.80 pg, mean corpuscular hemoglobin concentration ...
Mohamed F. Lutfi   +2 more
wiley   +1 more source

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