Results 281 to 290 of about 135,756 (330)

Detection of Germ Line p53 Mutations in Hereditary Cancer

Clinical Chemistry, 1992
openaire   +1 more source

Understanding antimicrobial use by equine owners in Wales: Using cross‐sectional survey and semi‐structured interviews

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobial resistance (AMR) is an increasingly serious threat to human and animal health. Antimicrobial use (AMU) in horses is gathering research interest, although there remain significant evidence gaps. Currently, there is scant qualitative research into equine owners' use of antimicrobials, specifically antibiotics, hindering ...
Rebekah B. Stuart, Fleur Miles‐Farrier, Alison M. Bard, Gwen Rees   +3 more
wiley   +1 more source

CRISPR/Cas9-based programmable genome editing in chickens: concepts, applications and regulatory issues. [PDF]

Front Genome Ed
Kolluri G, Naim A, Kumar Kurva S, Tyagi JS, Ansari MM, Tomar S, Tiwari AK, Chouhan L.   +7 more
europepmc   +1 more source

Biostimulants in plant brassinosteroid hormone receptor BRI1 activation—a new system to evaluate activation capacity

The FEBS Journal, EarlyView.
A novel assay evaluates plant biostimulants targeting the brassinosteroid receptor BRI1, a central component in plant growth and development. By expressing BRI1 in fission yeast, functional activation by brassinolide (BL) was enabled. Transcriptomic profiling identified BL‐responsive genes, leading to a GFP‐based reporter system. This platform offers a
Maribel Marquina, Montserrat Ricart‐Fort, Rocío Díaz‐Parra, Sandra López‐Avilés, Tula Yance, Pablo Quirós, Elena Contreras, Ignasi Salaet, Sergio Atares, Rosa Aligué   +9 more
wiley   +1 more source

Collective homeostasis of condensation-prone proteins via their mRNAs. [PDF]

Nature
Faraway R, Costello Heaven N, Digby H, Kuret Hodnik K, Rebselj J, Wilkins OG, Chakrabarti AM, Iosub IA, Vadnjal N, Dore R, Knez L, Ameres SL, Plaschka C, Ule J.   +13 more
europepmc   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

DMRT1 haploinsufficiency leads to secondary infertility in XY male rabbits†. [PDF]

Biol Reprod
Barka I, Dujardin E, Dewaele A, André M, Frambourg A, Thépot D, Jouneau L, Le Danvic C, Jolivet G, Pannetier M, Mandon-Pépin B, Pailhoux E.   +11 more
europepmc   +1 more source

The importin‐alpha superfamily engages in ethylene signaling by shuttling ETHYLENE INSENSITIVE 2 from the endoplasmic reticulum to the nucleus

The FEBS Journal, EarlyView.
The plant hormone ethylene regulates plant growth, ripening, senescence, and stress responses. The hormonal signal transmission, from receptors at the ER membrane to the transcriptional regulators in the nucleus, is still not completely understood.
Fabian Wynen, Jan Eric Maika, Raphael Josef Eberle, Nina Jahnke, Marcel Wiermer, Laura Hartmann, Rüdiger Simon, Georg Groth   +7 more
wiley   +1 more source

Stage- and tissue-specific gene editing using 4-OHT-inducible Cas9 in whole organism. [PDF]

J Cell Biol
Li Y, Zhang W, Wei Z, Li H, Liu X, Zheng T, Aziz T, Xing C, Meng A, Wu X.   +9 more
europepmc   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source